中国药物警戒 ›› 2011, Vol. 8 ›› Issue (10): 619-620.

• 药品不良反应监测 • 上一篇    下一篇

91例静脉滴注克林霉素不良反应分析

赵暄1, 郭婧2, 赵怀全1   

  1. 1 北京积水潭医院,北京 100035;
    2 首都医科大学附属复兴医院,北京 100045
  • 收稿日期:2011-01-28 出版日期:2011-10-10 发布日期:2015-07-30
  • 作者简介:赵暄,男,药师,医院药学。

Analysis of 91 Cases Adverse Reactions Caused by Intravenous Infusion of Clindamycin

ZHAO Xuan1GUO Jing2ZHAO Huai-quan1   

  1. 1 Beijng Jishuitan Hospital, Beijing 100035, China;
    2 Fu Xing Hospital, Capital Medical University, Beijing 100038, China
  • Received:2011-01-28 Online:2011-10-10 Published:2015-07-30

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摘要： 目的 了解和分析静脉滴注克林霉素所致药品不良反应的发生情况及相关的影响因素,为临床安全用药提供参考。方法 收集我院2004年12月至2010年12月向北京市药品不良反应监测网络上报的91例有关克林霉素的不良反应报告,对其进行统计、分析。结果 克林霉素所致不良反应临床表现较轻微,主要以皮肤及其附件损害,消化系统损害为主,联合用药易发生不良反应。结论 克林霉素临床应用中应严格掌握适应证和用法用量,注意患者过敏史、药品稳定性,并做好发生严重不良反应的对症处理。

关键词: 克林霉素, 不良反应

Abstract: Objective To study the characteristics of adverse drug reactions(ADR) caused by intravenous infusion of Clindamycin in our hospital and to provide reference for clinical medication. Methods 91 cases adverse reactions resulted from Clindamycin collected by Beijing ADR monitoring network from Dec, 2004 to Dec, 2010 in our hospital were analyzed statistically. Results The constant ADR induced by Clindamycin is slight. The occurrence of ADR is related to drug combination, Conclusion Clinical application of Clindamycin should be used to comply with the indication, to ask in detail about patients with a history of allergies and the stability of the medicine, to treat severe ADR occurred possibly.

Key words: clindamycin, adverse drug reactions(ADR)

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