中国药物警戒 ›› 2010, Vol. 7 ›› Issue (5): 303-305.

• 药品不良反应监测 • 上一篇    下一篇

86例药源性过敏性休克不良反应分析

王道祥, 江腊梅*, 王京娥, 刘武, 范伟   

  1. 济南市药品不良反应监测中心,山东 济南 250001
  • 收稿日期:2016-02-19 修回日期:2016-02-19 出版日期:2010-05-08 发布日期:2016-02-19
  • 通讯作者: 江腊梅,女,主任药师,药品医疗器械不良反应/事件监测。jianglamei@jnfda.gov.cn
  • 作者简介:王道祥,男,本科,药品检验与药品医疗器械不良反应/事件监测。

Analysis of 86 Reports of Drug-induced Anaphylactic Shock

WANG Dao-xiang, JING La-mei*, WANG Jing-e, LIU Wu, FAN Wei   

  1. Jinan City, Adverse Drug Reaction Monitoring Center, Shandong Jinan 250001
  • Received:2016-02-19 Revised:2016-02-19 Online:2010-05-08 Published:2016-02-19

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摘要： 目的 分析药源性过敏性休克发生的一般规律及抢救措施,为临床用药合理提供参考。方法 对济南市药品不良反应监测中心2007~2008年收到的86例过敏性休克病例报告进行回顾性分析。结果 抗微生物药品、中药注射剂的过敏性休克发生率居前2位;静脉用药发生率最高,占95.35％;过敏性休克大多数发生在用药后5分钟内,占39.53%;主要累及和损害循环系统、中枢神经、呼吸系统及全身。结论 临床应重视药源性过敏性休克的发生,用药前询问过敏史,严格用药指征,注意用药全程的监护,一旦出现不良反应及时停药,并采取适当措施予以对症抢救治疗。

关键词: 药品不良反应, 过敏性休克, 抢救, 分析

Abstract: Objective To analyze the general regularity and rescue measures of the drug-induced anaphylactic shock, provide references for clinical reasonable use of medicine. Methods 86 reports of anaphylactic shock were analyzed retro-spectively in Jinan adverse drug reaction mornitoring center from 2007 to 2008. Results Anti-microbial drugs and Traditional Chinese Medicine injections were the top two position. The highest incidence of intravenous drug, accounting for 95.35%. The majority of anaphylactic shock occurred within 5 minutes after administration, accounting for 39.53%. Mainly involve and damage included circulation, central nervous, respiratory and systemic. Conclusion The clinical should pay attention to drug-induced anaphylactic shock,strict indications medication, strengthen the guardianship medication.

Key words: adverse drug reaction(ADR), anaphylactic shock, resue, analysis

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