中国药物警戒 ›› 2010, Vol. 7 ›› Issue (11): 670-672.

• 管理及工作研究 • 上一篇    下一篇

解析医院开展药物警戒的重要性

崔岚1,傅文2,但国群3   

  1. 1.昆明医学院第二附属医院,云南昆明650101；
    2.云南省药品不良反应监测中心,云南昆明650101；
    3.昆明医学院药学院实习生,云南昆明650031
  • 收稿日期:2010-01-22 修回日期:2016-03-09 出版日期:2010-11-08 发布日期:2016-03-09
  • 作者简介:崔岚,女,主任药师,临床药学。

Analysis of Significance of Pharmacovigilance in Hospital

CUI Lan1, FU Wen2 ,DAN Guo Qun3   

  1. 1.The Second Affiliated Hospital of Kunming Medical College, Yunnan Kunming, 650101,China;
    2.The ADR Monitoring Center of Yunnan Province, Yunnan Kunming, 650101, China;
    3.Trainee in School of Pharmaceutical Sciences Kunming Medical College, Yunnan Kunming, 650031, China
  • Received:2010-01-22 Revised:2016-03-09 Online:2010-11-08 Published:2016-03-09

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摘要： 目的 了解医院药品不良反应/ 事件（ADR/ADE）发生）特点及一般规律,为临床合理用药提供参考。方法 采用回顾性研究方法,对某医院2006 年1 月至2008 年12 月收集到的237 份ADR/ADE 报告表进行统计分析。结果 在237例ADR/ADE 报告中,大于60岁年龄组的不良反应居首位,占24.47%；抗微生物药物不良反应居首位,占56.92%；静脉滴注给药引起的ADR/ADE 居首位,占75.10%；不良反应的临床表现以皮肤及其附件损害最多,占39.18%。结论 ADR/ADE 监测是医院的重要工作,开展药物警戒是患者用药安全的保障。

关键词: 药品不良反应/事件(ADR/ADE), 分析, 药物警戒

Abstract: Objective By analyzing the characteristicsand regulars of adverse drug reaction/event(ADR/ADE) occurred in one hospital, to provide reference for clinical rational drug use. Methods To adopt the reviewing analytical method to count up and analyze 237 cases ADR/ADE report,these ADR/ADE reports were received from Jan. 2006 to dec.2008 by one hospital. Results Out of the 237 cases ADR/ADE reports,58 showed ADR among the over 60 year old group, amount to 24.47%. Leading the list were antibiotics(56.92%).The clinical expression of ADR is showed mostly skin and appendix harms, amount to 39.18% .The suspected ADR cases induced by intravenous route were most common,amount to 75.10%. Conclusion ADR monitoring is an important work for medical institutions, and pharmacovigilance is conducive to patients' medication safety.

Key words: adverse drug reaction/event(ADR/ADE), analysis, pharmacovigilance

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