中国药物警戒 ›› 2020, Vol. 17 ›› Issue (8): 523-525.
DOI: 10.19803/j.1672-8629.2020.08.15

• 安全与合理用药 • 上一篇    下一篇

肿瘤化疗患者止吐药物临床应用分析

杨兰   

  1. 江苏省第二中医院药学部,江苏 南京210017
  • 收稿日期:2020-07-31 修回日期:2020-07-31 出版日期:2020-08-15 发布日期:2020-07-31
  • 作者简介:杨兰,女,主管药师,医院药学。

Clinical Application of Antiemetic Drugs to Tumor Chemotherapy Patients

YANG Lan   

  1. Department of Pharmacy, the Second Hospital of Jiangsu Province, Nanjing Jiangsu 210017, China
  • Received:2020-07-31 Revised:2020-07-31 Online:2020-08-15 Published:2020-07-31

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摘要： 目的 观察并研究肿瘤化疗患者使用止吐药的情况,为临床合理用药提供参考。方法 以2019年1月至7月期间在我院接受化疗并应用过止吐药的205例肿瘤患者为研究对象,对患者治疗过程中止吐药物的使用情况进行分析。结果 止吐药使用不合理主要是用药疗程不规范、用法用量不合理、联合用药不恰当以及超级别用药。结论 有少数患者存在不合理使用止吐药的情况, 其化疗所致恶心呕吐 (chemotherapy induced nausea and vomiting, CINV) 的控制率较合理使用止吐药的患者低。

关键词: 肿瘤化疗, 恶心呕吐, 止吐药, 合理用药

Abstract: Objective To observe and study the use of antiemetic drugs in tumor chemotherapy patients and to provide reference for clinical rational drug use. Methods Two hundred and five tumor patients who received chemotherapy and antiemetic drugs between January and July 2019 in our hospital were selected as subjects to analyze the use of anti-emetic drugs during treatment. Results The irrational use of antiemetic drugs was mainly manifested in the irregular course of medication, improper usage and dosage, unjustified combined medication and super-grade medication. Conclusion The control rate of CINV in a small number of patients with improper use of antiemetic drugs is lower than that of patients with proper use of antiemetic drugs.

Key words: tumor chemotherapy, nausea and vomiting, antemetic, rational drug use

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