Abstract: Objective To evaluate the pharmacodynamic effects of Yiye anti-influenza capsules (YYAFC). Methods The relieving fever effect was observed on Saccharomyces siccum induced fever model of rats; the analgesic effect was investigated by hot plate method and body twist method; the anti-inflammatory effect was observed by the capillary permeability augmentation of mice induced by acetic acid. Results High-dose and medial-dose of YYAFC could significantly decrease the raised body temperature caused by Saccharomyces siccum in rats, depress the torsion body of mice and increased the pain thresholds for 1 hour(P < 0.05). It also could significantly inhibit capillary permeability augmentation caused by acetic acid in mice. Conclusion YYAFC has better effects on relieving fever, analgesia and anti-inflammation.

Key words: Yiye anti-influenza capsules, relieving fever, analgesia, anti-inflammation