Abstract: In 2003, Medical Dictionary for Regulatory Activities(MedDRA) Maintenance and Support Services Organization (MSSO) established Standardised MedDRA Queries(SMQ), which is a collection of a number of MedDRA terms and the query strategy based on them. The purpose for SMQ is to help identify and retrieve potentially relevant cases. Adverse drug reactions in China have currently more than 3 million case reports. And when we carry out the risk assessment for drug safety based on this data, the accuracy and completeness of the query strategy is the basis of scientific assessments. This article is to analyze the background and detailed design of SMQ, and to explore the establishment of standardised query of adverse reaction terms.

Key words: standard, MedDRA, query