Chinese Journal of Pharmacovigilance ›› 2012, Vol. 9 ›› Issue (7): 385-386.

• Orginal Article •     Next Articles

Clinical Efficacy Analysis on Sodium Hyaluronate Combined with Compound Betamethasone in Treatment of Traumatic Synovitis of Knee Joint

NIU Shu-zhen   

  1. Niuzhuang Town Hospital of Dongying District, Dongying City of Shandong Province, Shandong Dongying 257086, China
  • Received:2012-03-01 Online:2012-07-10 Published:2015-08-07

Abstract: ObjectiveTo observe the clinical efficacy of sodium hyaluronate combined with compound betamethasone on the treatment of traumatic synovitis of knee joint under the method of knee articular cavity injection. Methods76 cases of traumatic synovitis of knee joint were randomly divided into two groups, the test group patients were given knee articular cavity injection once a week for 5 weeks, and sodium hyaluronate and compound betamethasone were given simultaneously during the 1st and 3rd week, only sodium hyaluronate was given during the 2nd, 4th and 5th week. Whereas the control group only received knee articular cavity injection of sodium hyaluronate once a week for 5 weeks. Observed the knee joint pain, swelling and joint effusion before and after treatment. ResultsThe relief of knee joint pain and improvement of knee joint function in test group were better than those in control group. ConclusionSodium hyaluronate combined with compound betamethasone by knee articular cavity injection is a safe and effective method for the treatment of traumatic synovitis of knee joint, especially for the patients with early or medium-term traumatic synovitis of knee joint, it is worthy to be recommended.

Key words: sodium hyaluronate, compound betamethasone, intra articular injection, traumatic synovitis of knee joint