Research Development on Chemical Composition in Herba Menthae Related with Efficacy and Toxicity

Abstract

Abstract: Objective Summarizing the current states of chemical composition of Herba Menthae related with its efficacy and toxicity, in order to identify its effective and toxical composition and offer the accordance and research ideas for further research on the relationship between efficacy, toxicity and chemical composition of Herba Menthae. Methods Ancient books and the related literatures in the recent years of Herba Menthae were collated, analyzed and summarized. Results Volatile oil are both the main material basis for efficacy and toxicity in Herba Menthae; the research about efficacy, material basis and toxicity of Herba Menthae is isolated and short of relevance. The research for its basis of extraction and separation technology research and quality control is also seldom-reported. Conclusion As a common-used record of TCM, Herba Menthae is urgent to be studied, based on the efficacy and chemicals related basic and "keep- efficacy" and "control- toxicity" research to provide experimental basement and literature reference for rational use in clinic.

Key words: Herba Menthae, efficacy, toxicity, chemical composition

CLC Number:

R285.5

HE Xi-wang, LI Xiao-yu, SUN Rong. Research Development on Chemical Composition in Herba Menthae Related with Efficacy and Toxicity[J]. Chinese Journal of Pharmacovigilance, 2011, 8(12): 746-749.

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