Abstract: Objective To analyze and summarize the adverse reactions or vent information of 465 traditional Chinese drugs Based on reported in the literature. Methods The reports in the literature of Chinese Crude Drug/Chinese Herbal Pieces were searched and analyzed by bibliometrics and statistic methods. Results The 1 256 reports about adverse reactions with 8 560 cases were collected, in the 465 Common Chinese Herbal Pieces. By analyzing again, It was found that 177 Chinese Herbal Pieces, 716 literatures, 2 208 clinical cases in the usage of convention and the correct route of administration. According to reported in the literature analysis, Chinese Crude Drug/Chinese Herbal Pieces adverse reactions take place mainly due to excessive doses, length time, in the process of Concocting and individual difference and so on. In the convention usage and dosage, Chinese Herbal Pieces reports of adverse reactions is relatively small, and mainly concentrated in the allergic population and is generally considered the drugs which were not regarded as adverse reactions. Fewer report adverse reactions about toxic traditional Chinese medicine was found, due to the results of all of its prevention. Conclusion I believe that the Chinese Crude Drug/Chinese Herbal Pieces of adverse reactions should be neither exaggerated nor ignored and should be an objective understanding and evaluation of Chinese Herbal Pieces of adverse reactions.

Key words: Chinese crude drug, Chinese herbal pieces, adverse reaction/event