Chinese Journal of Pharmacovigilance ›› 2011, Vol. 8 ›› Issue (11): 675-677.

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Progression of Material Basis Related to Angina Pectoris of Ligusticum chuanxiong Based on Efficacy and Pharmacology

GONG Yan-sheng1, LI Xiao-yu2, SUN Rong1, 3, *   

  1. 1 Shandong Research Academy of TCM, Shandong Jinan 250014, China;
    2 Shandong University of Traditional Chinese Medicine, Shandong Jinan 250355, China;
    3 Post-doctoral research center of TCM in Shandong University of Traditional Chinese Medicine, Shandong Jinan 250355, China
  • Received:2010-10-05 Online:2011-11-10 Published:2015-07-30

Abstract: Objective To summarizing the current states of material basis of Ligusticum chuanxiong, identify effective composition and its molecular mechanisms in Ligusticum chuanxiong related with angina pectoris, offer the accordance and research ideas for further research of Ligusticum chuanxiong. Methods The related references in recent 20 years about Ligusticum chuanxiong were analyzed, collated and summarized. Results The main compositions in Ligusticum chuanxiong related with angina pectoris are ligustilide, chuanxiongzine and ferulic acid. Research is almost on their pharmacological characteristics, but on molecular mechanisms is not deep enough. Conclusion Ligusticum chuanxiong has obvious therapeutic effect on angina pectoris. The effective composition and its molecular mechanisms related to angina pectoris are still at an initial stage.

Key words: Ligusticum chuanxiong, angina pectoris, material basis

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