Literature Review on 92 Cases of Adverse Reactions Induced by Octreotide

Abstract

Abstract: Objective Through investigating the characteristics and mechanism of adverse reactions induced by octreotide, to find its risk factors and provide technical support for safe and rational use of drugs in clinic. Methods Using "octreotide", "Sandostain", "Shanning", "adverse reaction"and "to"as key words to search and retrieve articles in the CNKI database, VIP Chinese full-text database and Wanfang database. 34 references which met the inclusion criteria were extracted and analyzed. Results Most of the reactions occurred in young and middle-aged patients. The major illness was pancreatitis. ADRs occurred more frequently within 24 h. Systems and organs mainly involved in adverse reactions were cardiovascular system damage, systemic lesion, etc. Arrhythmia and palpitation are the most commonly reported adverse reactions. Conclusion It is important to pay attention to the adverse reactions caused by octreotide, strengthen clinical rational use of drugs, in order to ensure the safe drug use in clinic.

Key words: octreotide, adverse drug reactions, literature review

CLC Number:

R994.11

XIE Wen-jing. Literature Review on 92 Cases of Adverse Reactions Induced by Octreotide[J]. Chinese Journal of Pharmacovigilance, 2017, 14(9): 551-554.

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