Chinese Journal of Pharmacovigilance ›› 2017, Vol. 14 ›› Issue (3): 186-188.

• Orginal Article • Previous Articles     Next Articles

Analysis of 502 Cases of Off-label Use of Breviscapine for Injection

XIAO Wang-zhong, DAI Bing*, OU YANG, Lin-qi, DENG Gui-ming, HUANG Li, GUO Yu-ge   

  1. First Hospital of Hunan University of Chinese Medicine, Hunan Changsha 410001, China
  • Received:2017-04-20 Revised:2017-04-20 Online:2017-03-20 Published:2017-04-20

Abstract: Objective To understand the off-label use of breviscapine for injection in clinic, promote reasonable application of traditional Chinese medicine injection. Methods 502 medical records of hospitalized patients using breviscapine for injection in 2015 were retrospectively analyzed. Results There were 241 cases for off-label indications, 23 cases for overdosage, 34 cases for off-label concentration, and 7 cases for improper frequency, involving 18 cases in children. Conclusion The off-label use of breviscapine for injection in clinic affects patients’ medication safety. It is suggested that the use of TCM injection should keep in accordance with its instruction strictly.

Key words: breviscapine injection, off-label, medicine safety

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