Abstract: Objective To investigate rational use of antibiotics at perioperative period in orthopedics department and evaluate the effect of the plan , do , check and action ( PDCA ) cycle management. Methods According to PDCA procedure,materials were collected and analyzed, and measures were made out on promotion followed by supervising the practice for furhter improvement. The data of medication of type I and II incision operation were collected and compared from January to July in 2011 (before the implementation of PDCA method) and from January to July in 2012 ( after the implementation of PDCA method). Results After implementatcion of PDCA method , application rate of antibiotics decreased from 100% to 68% and the average cost of antibiotics declined from1 107.6 yuan to 348.3 yuan.The rational application of antibiotics was significantly improved. Conclusion The implementation of PDCA method is feasible and effective, which can improve the rational application of antibiotics at perioperative period in orthopedics department.

Key words: PDCA cycle, perioperative period, antibiotics, rational use