Abstract: Objective Based on a survey of the prescriptions of community health service centers in some cities and some rural hospitals of Liaoning Province and an analysis of grassroots of irrational drug use of some health institutions, this report tries to provide accurate data and countermeasures to promote the rational clinical application of drugs.Methods The report conducts the research using the following Methods: extracting prescriptions of health institutions randomly in 2007, and transcribing them in the survey forms, and then analyzing the rational drug use according to WHO(World Health Organization) index. Results The following problems exist in health institutions: the number and costs of average prescribed medicines are high; the use of basic drugs is low; the use of antibiotics, hormones, injections is not rational; there exists the irregular and irrational phenomena of combination of various drugs, among which the phenomenon in rural hospitals is more serious. Conclusion The health institutions shall further enhance the rational drug use level to ensure the public of their secure, economic and effective drug use.

Key words: health institutions, rational drug use, intervention measures