Chinese Journal of Pharmacovigilance ›› 2012, Vol. 9 ›› Issue (8): 485-486.

• Orginal Article • Previous Articles     Next Articles

Analysis of 112 cases of Adverse Drug Reactions Induced by Antihypertensive Drugs

LI Lei   

  1. Pharmaceutical department of Hefei first people hospital, Anhui Hefei 230061, China
  • Received:2011-09-27 Online:2012-08-10 Published:2015-08-07

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Abstract: ObjectiveTo discuss the features of adverse drug reaction(ADR) induced by antihypertensive drugs in order to promote the safe drug use in clinic. MethodsThe ADRs induced by antihypertensive drugs were searched between Jan. 2007 and Dec. 2010 in our hospital, and statistical analysis was made. ResultsThe statistics showed 112 cases ADR were induced by antihypertensive drugs and took 5.9% of all the ADR reports in the same period. The female cases were more than the males and the incidence between 70~90 was the highest. CCB and ACEI had more cases. The serious ADRs were 4 cases, most of which were caused by an old drug reserpine. ConclusionMore attention should be paid to ADR of antihypertensive drugs and drugs with severe ADRs should be obsoleted to reduce the ADRs.

Key words: antihypertensive drugs, ADR