Abstract: Objective Understand the status of antibacterial drug use and administration at hospitals of China, identify the problems in the process of use, and put forward the feasible suggestions. Methodse A sampling investigation was carried out on the antibacterial rational drug use indicators of antibiotics at 15 hospitals of Beijing, Shanghai, Guangzhou and Chengdu. Data statistics was analyzed by SPSS11.0 software. Results The average frequency of antibacterial drug use for non-surgical inpatients at 15 grade-3 hospitals is 49.1%, while for surgical inpatients, the average is 94.6%. In the inpatients who used antibacterial drugs, the average number of categories is 2. The average cost of antibacterial drugs for inpatients is 970.7 Yuan, accounting for 27.8% of the total cost of all drugs. The average duration of therapy with antibacterial drugs is 5.8 days. The average number of days at hospital is 16.8 days. The ratio of patients receiving antibacterial drug-sensitivity tests is 9.7%. The average number of antibacterial drug use for outpatients is 2.5.The average percentage of antibacterial drug use is 21.9%. The average percentage of injection use is 10.4%. The average cost of drugs is 200.3 Yuan. Conclusion Using the international rational drug use indicators of antibacterial drugs can evaluate the antibacterial drug use level Objectively and scientifically, provide evidence for intervention, offer reference for the monitoring of antibacterial drug use indicators.

Key words: antibacterial drugs, international indicators, rational drug use