Research progress in drug-pair compatibility principles of Psoraleae Fructus based on theories of seven features of compatibility

doi:10.19803/j.1672-8629.20230758

Abstract

Abstract: Objective To summarize the research progress related to Psoraleae Fructus drug pairs based on the theory of seven features of compatibility, and provide data for rational clinical applications of Psoraleae Fructus. Methods Through literature research and analysis, the research progress concerning Psoraleae Fructus drug pairs was summarized in terms of mutual reinforcement/assistnce, synergistic effect enhancement, mutual restraint/suppression, reduction of toxicity and side effects, and compatibility contraindications. Results Based on theories of seven features of compatibility and on studies of clinical medication principle of Psoraleae Fructus drug pairs, it was found that the mutually-reinforcing and mutually-assisting herb pairs of Psoraleae Fructus included Myristicae Semen, Cnidh Fructus, Foeniculi Fructus, Alpiniae Oxyphyllae Fructus, Cinnamomi Cortex, Euodiae Fructus, Morindae Officinalis Radix, Eucommiae Cortex, Drynariae Rhizoma and Curculiginis Rhizoma while the mutually-restricting and mutually-suppressing herb pairs included Juglandis Semen, Rehmanniae Radix, Schisandrae Chinensis Fructus, Paeoniae Radix Rubra. The mutually-inhibiting and mutually-antagonizing herb pairs included Glycyrrhizae Radix Et Rhizoma and Epimedii Folium. Conclusion This article summarizes the drug pairs that are often compatible with Psoraleae Fructus, providing ideas for clinical prescriptions.

Key words: seven emotions of Chinese materia medica, compatibility, drug pairs, Psoraleae Fructus, increasing efficiency, detoxification, overall concept

CLC Number:

R994.11

WANG Xiaoyan, CHEN Xiaofei, ZHANG Hui, ZHANG Mingliang, WU Yali, YANG Liuqing, TANG Jinfa, LI Weixia. Research progress in drug-pair compatibility principles of Psoraleae Fructus based on theories of seven features of compatibility[J]. Chinese Journal of Pharmacovigilance, 2024, 21(5): 594-600.

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