Literature analysis of adverse drug reactions induced by posterior pituitary injection

doi:10.19803/j.1672-8629.2022.01.21

Abstract

Abstract: Objective To study the pattern, characteristics and influencing factors of adverse reactions induced by posterior pituitary injection so as to provide reference for clinical safe medication. Methods Based on such key words as“pituitrin injection”and“adverse reactions”, literature was searched for that was related to the adverse reactions caused by pituitrin injection reported in CNKI, VIP and Wanfang databases between inception and April 30, 2019. According to the inclusion and exclusion criteria, 159 articles were included for data retrieval and statistical analysis. Results The adverse reactions involved multiple organs and systems. The most common reactions were hyponatremia and gastrointestinal tract damage. In severe cases, hyponatremia encephalopathy and cardiac arrest were likely. Conclusion The adverse reactions caused by posterior pituitary injection deserve attention, and efforts have to be made to guard against the occurrence of adverse reactions to ensure the safety of clinical medication.

Key words: posterior pituitary injection, adverse drug reactions, hyponatremia, gastrointestinal tract damage

CLC Number:

XIE Xiaoyan, XIA Xudong, YANG Xue, LI Qingfang, LIU Cuili, CHEN Shiwei. Literature analysis of adverse drug reactions induced by posterior pituitary injection[J]. Chinese Journal of Pharmacovigilance, 2022, 19(1): 95-99.

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