Chinese Journal of Pharmacovigilance ›› 2023, Vol. 20 ›› Issue (1): 110-116.
DOI: 10.19803/j.1672-8629.20211165

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Research progress in substances related to hemolysis risk in glucose-6-phosphate dehydrogenase deficiency

LI Jinying1,2, SONG Hongjie3, LI Jinqi1,2, GU Haihui1,2, QIAN Baohua1,2,*   

  1. 1Department of Transfusion Medicine, Shanghai 200433, China;
    2PLA Research & Innovation Base of Pediatric Hemolytic Anemia, Shanghai 200433, China;
    3Department of Pharmacy, the First Affiliated Hospital of Naval Medical University, Shanghai 200433, China
  • Received:2021-01-14 Published:2023-01-19

Abstract: Drug-induced hemolysis is one of the common causes of acute hemolysis in glucose-6-phosphate dehydrogenase deficiency (G6PDd). With the development and marketing of new drugs, cases of drug-induced hemolysis in G6PDd are increasing year by year. This paper lists and updates antibiotics, antivirals, antineoplastics, antipyretics, anti-inflammatory drugs, metabolic drugs, vasodilators, anaesthetics, antidotes, other drugs, herbs, plants, topical drugs, reagents, chemicals and food with hemolysis risk for G6PDd so as to facilitate clinical selection of treatments and warning and prevention of this disease.

Key words: glucose-6-phosphate dehydrogenase deficiency, hemolysis risk, methemoglobinemia, drugs, chemical, food

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