The research development of inoculation safety associated with licensed HPV vaccines in China

doi:10.19803/j.1672-8629.20211075

Abstract

Abstract: Objective To review the inoculation information of licensed human papilloma virus (HPV) vaccines in China, so as to provide reference for the safety of HPV vaccine inoculation. Methods We did a systemic discussion based on the types of vaccine, the status quo of inoculation, and the safety studies of the licensed vaccines in China. Focus on the development of surveillance and research for the safety of vaccination, and then put forward targeted opinions and suggestions for future HPV prevention. Results Four HPV vaccines (i.e., Cervarix, Gardasil, Gardasil 9, and Cecolin) have been licensed in China, and their vaccination coverage rates are increasing year by year. The feedback of vaccination safety was mainly from three measures: active surveillance, passive surveillance, and observational studies. Conclusion The safety evaluation for licensed HPV vaccines has great significance to improve inoculation safety and increase vaccination coverage rate. The existing safety studies are still stay in data statistical processing, more in-depth analytical methods and researches need to be implemented.

Key words: human papilloma virus (HPV), cervical cancer, vaccine, safety, adverse event

CLC Number:

ZI Wenrui, YANG Qiuyue, SU Jun, XIE Jiang'an. The research development of inoculation safety associated with licensed HPV vaccines in China[J]. Chinese Journal of Pharmacovigilance, 2023, 20(3): 311-316.

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