Chinese Journal of Pharmacovigilance ›› 2021, Vol. 18 ›› Issue (9): 883-886.
DOI: 10.19803/j.1672-8629.2021.09.19

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Clinical Characteristics and Rationality of Medication among IgA Nephropathy Outpatients in a Rehabilitation Center

SHEN Jingping   

  1. Beidaihe Rehabilitation Center, Qinhuangdao Hebei 066100, China
  • Received:2021-05-21 Online:2021-09-15 Published:2021-09-18

Abstract: Objective To find out about the drug composition, characteristics of medication and rationality of prescriptions among patients with IgA nephropathy so as to provide reference for clinical rational drug use. Methods From January 1, 2018 to December 31, 2019, 18 6111 prescriptions for nephrotic outpatients and 809 148 medication orders were collected, including 4 326 prescriptions and 13 542 medication orders for IgA nephropathy. The drug categories, dosage and composition of different drug categories specified in prescriptions for IgA nephropathy were statistically analyzed. Results The proportion of traditional Chinese medicine and Chinese patent medicine was much higher than that of chemical medicine and western medicine (78.4% vs 21.6%). Chinese patent medicine was mainly used for IgA nephropathy, supplemented by drugs that could invigorate the spleen and kidney, clear heat and detoxification, and tonify the lung and kidney. Chemical medicine and western medicine were mainly used to reduce proteinuria and blood pressure. It was found that there were 73 improper prescriptions, accounting for 1.7% of the total, which were mainly manifested as nonstandard prescription writing and prescriptions of inappropriate drugs. Conclusion Traditional Chinese medicine is combined with western medicine in the treatment of IgA nephropathy in our hospital, and medication is basically well-grounded. The proportion of traditional Chinese medicine and traditional Chinese patent medicine is high, but there are cases of irrational medication. It is critical to keep an eye on prescriptions and standardize clinical medications.

Key words: nephropathy, IgA nephropathy, outpatients, medication analysis

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