Potential Risks of Salviae Miltiorrhizae and Ligustrazine Injection

doi:10.19803/j.1672-8629.2021.06.17

Abstract

Abstract: Objective To investigate the potential risks of Salviae Miltiorrhizae and Ligustrazine injection so as to promote rational use in clinical practice. Methods The valid data of Salviae Miltiorrhizae and Ligustrazine injection was retrieved from the database of National Center for Adverse Drug Reaction Monitoring and literature. The clinical applications and potential risks of this injection were analyzed. Results Salviae Miltiorrhizae and Ligustrazine injection was widely used in clinic. Both the number of adverse reactions reported and the proportion of serious reports were trending up. Additionally, off-label use and overdose were common, which might increase the incidence of adverse reactions in patients. Conclusion Salviae Miltiorrhizae and Ligustrazine injection should be used in accordance with indications. Meanwhile,close attention should be paid to the risk of serious allergic reactions, especially anaphylactic shock.

Key words: Salviae Miltiorrhizae and Ligustrazine, allergic reaction, adverse drug reaction

CLC Number:

R979.1

XU Xianxing, YANG Jingwen, MIAO Huiqing. Potential Risks of Salviae Miltiorrhizae and Ligustrazine Injection[J]. Chinese Journal of Pharmacovigilance, 2021, 18(6): 575-578.

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