Abstract: Objective To analyze the usage of pregnancy termination drugs in a Maternal and Child Health Hospital, and probe its rationality so as to provide data for clinical rational drug application. Methods The prescription automatic screening system (PASS) and HIS system were used to retrieve data from medical records, involving 100 records of outpatients and emergency patients and 50 hospitalizations in 2017 and 2018. The clinical diagnosis, usage and dosage, combined use and improper use of drugs for termination of pregnancy were analyzed after the data of eight quarters was summarized. Results The average age of 1,200 randomly selected patients who used drugs for terminating pregnancy was (29.0±5.24)y. In addition to early induced abortion and middle//late pregnancy induced labor, other diagnoses involving drug pregnancy termination accounted for 29.25%, such as missed abortion, postoperative and ectopic pregnancy. Common drugs used in combination with pregnancy termination drugs included Chinese patent medicines, antimicrobial agents, estrogen and progesterone drugs (contraceptives), intraoperative medications and drugs for the prevention/treatment of postpartum bleeding. The irrational usage of drugs for termination of pregnancy mainly involved inappropriate drug usage and dosage, accounting for 48.5%. Conclusion From 2017 to 2018, the percentage of rational use of pregnancy termination drugs in our hospital gradually increased from 80.67% to 97.33%, but there are still cases of irrational use, which should be improved continuously.

Key words: induced abortion, pregnancy termination drugs, analysis of clinical medication, rational drug use