Study of VigiBase Database of Uppsala Monitoring Centre

doi:10.19803/j.1672-8629.2020.10.06

Abstract

Abstract: Objective To study the structure, tools and functions of VigiBase, a database managed by the Uppsala Monitoring Centre (UMC), and to provide reference for improving the database of adverse drug reactions (ADRs) in China. Methods The structure and functions of VigiBase were analyzed by consulting literature and searching VigiBase. Results VigiBase was the largest database of individual case safety reports (ICSRs) in the world. UMC evaluated the quality of ICSRs via VigiGrade, inspected the duplicate reports via VigiMatch, detected drug safety signals via VigiRank, and also provided VigiLyze, VigiFlow, VigiAccess and other tools for member states to manage ICSRs and retrieve data from VigiBase. Conclusion The assessment of report quality and drug safety signal detection need to be improved in China.

Key words: WHO programme for international drug monitoring, Uppsala Monitoring Centre, database, vigivase database

CLC Number:

R951

ZHANG Wei, WEI Fuqian, YANG Yue. Study of VigiBase Database of Uppsala Monitoring Centre[J]. Chinese Journal of Pharmacovigilance, 2020, 17(10): 676-680.

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