Abstract: Objective To provide a reference for promoting the rational use of antibacterial drugs against respiratory infections. Methods The paper collected 25% of irrational prescriptions of antibacterial drugs for respiratory infections by outpatient and emergency physicians from July, 2018 to December, 2019. According to the constituent of irrational prescriptions, the classification and statistical analysis on the constituents of irrational drugs use was made by Excel 2017, showing the major and minor factors by Pareto chart. Results Among 7,937 antibacterial prescriptions in total, 226 were irrational, accounting for 2.85%. The age distribution of irrational prescriptions is mainly between 20 and 60 years old, mainly from emergency department of fever, cardiology, respiratory department, geriatrics, pediatrics, emergency department and endocrinology department. Inappropriate indications and dosages was the major factor of irrational prescriptions, constituting for 80.09%.while the unsuitable drug selection was the minor factor, constituting for 89.18%. Conclusion There are many problems in the use of antibacterial drugs. According to the main departments and age distribution of irrational prescriptions, targeted prescription reviews should be adopted. Moreover, drugs safety warnings should be issued for problems that occurred frequently, and the treatment plan should be continuously optimized, in order to ensure the rational use of antibacterial drugs in emergency and outpatient departments.

Key words: respiratory infections, antibacterial, analysis, irrational medication