1270 Cases of Adverse Drug Reactions Induced by Acanthopanax Injection

doi:10.19803/j.1672-8629.2020.07.09

Abstract

Abstract: Objective To analyze the safety of acanthopanax injection used in Sichuan Province, and explore the patterns and characteristics of adverse reactions induced by acanthopanax injection in order to provide technical support for safe and rational use of drugs in clinic. Methods A total of 1 270 cases of adverse reactions induced by acanthopanax injection collected between January 1, 2014 and August 31, 2019 were retrospectively studied and statistically analyzed. Results According to the information on monitoring, the ADRs of acanthopanax injection mostly occurred in middle-aged and elderly patients over 45 years old, and most of the ADRs occurred in the first 30 minutes after medication, involving a wide range of organs and systems. The main ADRs were skin and accessory lesions, systemic damage, respiratory damage, cardiovascular damage, gastrointestinal damage, nervous system damage, vascular damage and coagulopathy, damage to the injection site, immune dysfunction and infection . Prompt interventions in ADRs could help alleviate or cure the symptoms. Conclusion Attention should be paid to safe and rational use of acanthopanax injection. Clinical nursing and monitoring of adverse drug reactions have to be enhanced to prevent over-indications and over-dosage medication.

Key words: acanthopanax injection, adverse drug reactions（ADRs）, analysis

CLC Number:

R969.3

WEN Xiaoling, ZHANG Yan, LAN Shan. 1270 Cases of Adverse Drug Reactions Induced by Acanthopanax Injection[J]. Chinese Journal of Pharmacovigilance, 2020, 17(7): 425-430.

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