Abstract: Objective To generate a technology readiness evaluation mechanism suitable for drug R & D and safety management in China. Methods The evaluation standards and methods of biomedical technology readiness level(BTRL) in the United States are studied and analyzed. Combined with the characteristics of drug discovery, supervision and industrialization in China, the technology readiness level and indicators in China are put forward, and an empirical analysis in the major R&D project of new drug discovery are performed. Results and Conclusion Through the research, the evaluation method of technology readiness level of chemical drugs and biological drugs in China are established. The evaluation method provides management and evaluation tools of scientific research projects, R&D and safety control in China, which also provides reference for other industries.

Key words: biomedical technology readiness level (BTRL), drug discovery, project management