Chinese Journal of Pharmacovigilance ›› 2020, Vol. 17 ›› Issue (3): 129-135.
DOI: 10.19803/j.1672-8629.2020.03.01

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Present Situation and Prospect of Antiviral Treatments for COVID-19

TIAN Di, WANG Lin, GE Ziruo, CUI Shuping, CHEN Zhihai*   

  1. Department of Infectious Diseases, the National Clinical Key Department of Infectious Diseases, Beijing Key Laboratory Emerging Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
  • Received:2020-03-17 Revised:2020-03-17 Online:2020-03-15 Published:2020-03-17

Abstract: In December 2019, a series of pneumonia cases of unknown cause emerged in Wuhan, Hubei Province. In January 2020, a new type of coronavirus (2019-nCoV) was isolated. With the outbreak of COVID-19, the number of severe, critical and death cases is increasing gradually. In the diagnosis and treatment program of our country, the oral administration of lopinavir/ritonavir and the atomization of α-interferon were used, and ribavirin, chloroquine phosphate and abidol can also be used for antiviral treatment.The plasma of convalescent patients can be used for the treatment of severe and critical patients. Recently, a United States report that the first case of 2019-nCoV infection confirmed patient have been significantly improved after treatment with remdesivir. Fabiravir is also considered to have potential efficacy. Antiviral treatment is the key to the treatment of severe and critical diseases. In this paper, the present situation and prospect of selective antiviral treatments for COVID-19 is reviewed.

Key words: COVID-19, antiviral treatments

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