中国药物警戒 ›› 2015, Vol. 12 ›› Issue (6): 373-375.

• 医院药事管理与合理用药 • 上一篇    下一篇

某院质子泵抑制剂预防应激性溃疡的合理性分析

沈驰1,刘娜1*   

  1. 1四川省科学城医院药剂科，四川 绵阳 621900;
    2西安交通大学第二附属医院药剂科，陕西 西安 710000
  • 收稿日期:2015-03-05 出版日期:2015-06-08 发布日期:2015-07-27
  • 通讯作者: 刘娜，女，博士，主管药师，临床药学。
  • 作者简介:沈驰，男，药师，临床药学。

Reasonability Analysis of Proton Pump Inhibitors for Stress Ulcer in a Hospital

SHEN Chi1,LIU Na2*   

  1. 1Department of Pharmacy, Sichuan Science City Hospital, Sichuan Mianyang 621900, China;
    2Department of Pharmacy, Second Affiliated Hospital of Xi'an Jiaotong University, Shanxi Xi'an 710000, China
  • Received:2015-03-05 Online:2015-06-08 Published:2015-07-27

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摘要： 目的 通过分析某院质子泵抑制剂在预防应激性溃疡中的使用情况，指导预防应激性溃疡的合理用药。方法 随机抽取某院2014年1～6月消化内科等8个临床科室有使用质子泵抑制剂的病历240份，从预防应激性溃疡的角度，对其适应证、用药品种、用法用量、用药时间方面进行合理性评价分析。结果 预防性使用质子泵抑制剂的共115份，占总数47.91%，其中不合理的有59份，占预防用药的51.30%，主要表现在无指征预防用药和用药疗程过长。结论 某院质子泵抑制剂的预防性使用存在不合理的现象，医院相关部门应并加大对此监督和管理。

关键词: 质子泵抑制剂, 应激性溃疡, 合理用药

Abstract: Objective To analyze the situation of proton pump inhibitors for stress ulcer in a hospital and instruct the rational application of the drug. Methods 240 medical records of patients from 8 clinical departments including department of gastroenterology which used PPIs from January to June 2014 were randomly chosen. What used for preventing stress ulcer were sampled for the evaluation of indications in prophylactic medication, the variety of drug, usage and dosage, course of treatment. Results There were 115 copies(47.91%)which used PPIs for preventing stress ulcer, 59 copies of them(51.30%)were unreasonable. No indications and long course of treatment were the main problems. Conclusion There are still some unreasonable situations on the prophylactic use of PPIs in a hospital, the related departments should strengthen the supervision and management.

Key words: proton pump inhibitors, stress ulcer, rational drug use

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