中国药物警戒 ›› 2012, Vol. 9 ›› Issue (4): 244-246.

• 药品不良反应监测 • 上一篇    下一篇

42例注射用酒石酸吉他霉素不良反应分析

范平平   

  1. 大连市药品不良反应监测中心，辽宁 大连 116021
  • 收稿日期:2011-12-30 出版日期:2012-04-10 发布日期:2015-08-10
  • 作者简介:范平平，女，药师，药品不良反应监测。

Analysis of 42 Cases of Adverse Reactions Caused by Kitasamycin for Injection

FAN Ping-ping   

  1. Dalian Adverse Drug Reaction Monitoring Center, Liaoning Dalian 116021, China
  • Received:2011-12-30 Online:2012-04-10 Published:2015-08-10

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摘要： 目的探讨注射用酒石酸吉他霉素所致药品不良反应的发生特点及影响因素，为临床安全用药提供参考。方法对大连市药品不良反应监测中心2009年1月至2011年12月收集到的42例注射用酒石酸吉他霉素所致的药品不良反应进行统计分析。结果注射用酒石酸吉他霉素所致不良反应多发生在首次用药过程中，老年患者不良反应发生率较高，说明书中未记载的不良反应所占比例较大，其中中枢及外周神经系统损害最为常见。结论注射用酒石酸吉他霉素应在用药前试敏，用药过程中密切监测，发生不良反应及时采取措施，尽量减少或避免不良反应对患者造成损害。

关键词: 注射用酒石酸吉他霉素, 不良反应, 报告分析

Abstract: Objective To investigate the characteristics of adverse drug reactions(ADR) caused by kitasamycin for injection,and provide references of clinical rational and safe use of drug. Methods 42 ADR cases collected in Dalian Medicine Adverse Reaction Monitoring Center from Jan.2009 to Dec. 2011 were analyzed retrospectively. Results Most ADR happened during the first time using kitasamycin for injection, aged patients have a higher incidence. Parts of ADR are not recorded in the drug instructions, central and peripheral nervous system damage most frequently occurs. Conclusion Skin test must be taken before using kitasamycin for injection, medical workers should pay more attention to the patients, and take measures in time when ADR happen.

Key words: kitasamycin for Injection, adverse drug reactions(ADR), analysis of reports