

中国药物警戒 ›› 2019, Vol. 16 ›› Issue (12): 762-764.
DOI: 10.19803/j.1672-8629.2019.12.12
徐银莹, 姜孙旻
收稿日期:2019-12-18
修回日期:2019-12-18
出版日期:2019-12-15
发布日期:2019-12-18
通讯作者:
*姜孙旻,女,硕士,主管药师,临床药学。
作者简介:徐银莹,女,本科,主管药师,临床药学。
基金资助:XU Yinying, JIANG Sunmin
Received:2019-12-18
Revised:2019-12-18
Online:2019-12-15
Published:2019-12-18
中图分类号:
徐银莹, 姜孙旻. 奥拉帕尼片致肝损伤1例[J]. 中国药物警戒, 2019, 16(12): 762-764.
XU Yinying, JIANG Sunmin. One Case of Hepatic Dysfunction Induced by Olaparib Tablets[J]. Chinese Journal of Pharmacovigilance, 2019, 16(12): 762-764.
| [1] 于乐成, 茅益民, 陈成伟. 药物性肝损伤诊治指南[J].中华肝脏病杂志, 2015, 23(10):1752-1769. [2] 刘建平, 邢建民. 循证的药品不良反应评价方法[J]. 中国药物警戒, 2010, 7(1):12-15. [3] Moore Kathleen, Colombo Nicoletta, Scambia Giovanni,et al.Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer[J]. N Engl J Med, 2018, 379(26):2495-2505. [4] Friedlander Michael, Matulonis Ursula, Gourley Charlie,et al.Long-term efficacy, tolerability and overall survival in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer treated with maintenance olaparib capsules following response to chemotherapy[J]. Br J Cancer,2018, 119(9):1075-1085. [5] Moore K N, Monk B J.Patient Counseling and Management of Symptoms During Olaparib Therapy for Recurrent Ovarian Cancer[J]. Oncologist, 2016, 21(8):954-63. [6] Pujadelauraine E, Ledermann J A, Selle F, et al.Olaparib tablets as maintenance therapy in patients with platinum-sensitive,relapsed ovarian cancer and a BRCA1/2 mutation(SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial[J]. Lancet Oncol, 2017, 18(9):1274-1284. [7] Robson Mark, Im Seock-Ah, Senkus Elżbieta, et al.Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation[J]. N Engl J Med, 2017,377(6): 523-533. [8] Bang Yung-Jue, Xu Rui-Hua, Chin Keisho, et al.Olaparib in combination with paclitaxel in patients with advanced gastric cancer who have progressed following first-line therapy (GOLD): a double-blind, randomised, placebo-controlled, phase 3 trial[J]. Lancet Oncol, 2017, 18(12):1637-1651. [9] Ledermann Jonathan A, Harter Philipp, Gourley Charlie,et al.Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib main tenance monotherapy: an updated analysis from a randomised,placebo-controlled, double-blind, phase 2 trial[J]. Lancet Oncol, 2016, 17(11): 1579-1589. [10] Oza Amit M, Cibula David, Benzaquen Ana Oaknin, et al.Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial[J]. Lancet Oncol, 2015, 16(1):87-97. [11] Kaufman B, Shapirafrommer R, Schmutzler R K, et al.Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation[J]. J Clin Oncol,2015, 33(3):244-50. [12] Domchek S M, Aghajanian C, Shapira-Frommer R, et al.Efficacy and safety of olaparib monotherapy in germline BRCA1/2 mutation carriers with advanced ovarian cancer and three or more lines of prior therapy[J]. Gynecol Oncol,2016, 140(2):199-203. [13] Liu J F, Barry W T, Birrer M, et al.Combination cediranib and olaparib versus olaparib alone for women with recurrent platinum-sensitive ovarian cancer: a randomised phase 2 study[J]. Lancet Oncol, 2014, 15(11):1207-1214. [14] Del Conte G, Sessa C, Von Moos R, et al.Phase I study of olaparib in combination with liposomal doxorubicin in patients with advanced solid tumours[J]. Br J Cancer, 2014, 111(4):651-659. [15] Balmana J, Tung N M, Isakoff S J, et al.Phase I trial of olaparib in combination with cisplatin for the treatment of patients with advanced breast, ovarian and other solid tumors[J]. Ann Oncol, 2014, 25(8):1656-1663. [16] Choy Edwin, Butrynski James E, Harmon David C, et al.Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy[J].BMC Cancer, 2014, 14(1):1-6. [17] Ledermann Jonathan, Harter Philipp, Gourley Charlie, et al.Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial[J]. Lancet Oncol, 2014, 15(8):852-861. [18] Sandhu S K, Omlin A, Hylands L, et al.Poly (ADP-ribose)polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer[J]. Ann Oncol,2013, 24(5):1416-1418. [19] Samol J, Ranson M, Scott E, et al.Safety and tolerability of the poly(ADP-ribose) polymerase (PARP) inhibitor, olaparib (AZD2281) in combination with topotecan for the treatment of patients with advanced solid tumors: a phase I study[J].Invest New Drugs, 2012, 30(4):1493-1500. [20] Ledermann J, Harter P, Gourley C, et al.Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer[J].N Engl J Med, 2012, 366(15):1382-1392. [21] Kaye S B, Lubinski J, Matulonis U, et al.Phase II, open-label,randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor,and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer[J]. J Clin Oncol, 2012, 30(4):372-379. [22] Khan O A, Gore M, Lorigan P, et al.A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436)and dacarbazine in patients with advanced solid tumours[J].Br J Cancer, 2011, 104(5):750-755. [23] Liu J, Fleming G F, Tolaney S M, et al.A phase I trial of the PARP inhibitor olaparib (AZD2281) in combination with the antiangiogenic cediranib (AZD2171) in recurrent ovarian or triple-negative breast cancer[J]. J Clin Oncol, 2011, 29(15):5028-5028. |
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