中国药物警戒 ›› 2019, Vol. 16 ›› Issue (4): 228-230.

• 安全性评价与合理用药 • 上一篇    下一篇

1例急性白血病重症感染伴尖端扭转性室速患者的药学监护

张俊忠1, 张志超2   

  1. 1濮阳市人民医院药剂科,河南 濮阳 457000;
    2福建医科大学,福建 福州 350004
  • 收稿日期:2019-05-09 修回日期:2019-05-09 出版日期:2019-04-20 发布日期:2019-05-09
  • 作者简介:张俊忠,男,副主任药师,临床药学。

Pharmaceutical Care for One Case of Acute Leukemia Severe Infection with Torsade de Pointes

ZHANG Junzhong1, ZHANG Zhichao2   

  1. 1 Department of Pharmacy, People's Hospital of Puyang, Henan Province,Henan Puyang 457000, China;
    2Fujian Medical University, Fujian Fuzhou 350004, China
  • Received:2019-05-09 Revised:2019-05-09 Online:2019-04-20 Published:2019-05-09

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摘要： 目的 通过急性白血病化疗后重症感染伴尖端扭转性室速患者的药物治疗,探讨重症感染合并心功能异常患者药学监护切入点。方法 临床药师参与1例急性白血病化疗后继发重症感染伴尖端扭转性室速患者的治疗过程,协助临床医师制定个体化治疗方案,并对主要药物治疗实施药学监护。结果 临床药师协助医师调整用药方案,对药品不良反应采取有效干预措施,提高临床药物治疗水平。结论 临床药师深入临床,以药学专业知识为切入点,提供及时合理的药学监护,保障患者用药安全有效。

关键词: 伏立康唑, 低钾血症, 尖端扭转性室速, 药学监护

Abstract: Objective To analyze the drug treatment of severe infection with torsade de pointes(TdP), so as to investigate the method of pharmaceutical care. Methods Clinical pharmacists were active in the whole process of 1 case of secondary severe infection with TdP, assisted physicians to develop individualized therapeutic regimen and delivered special pharmaceutical care in main drug therapy. Results Clinical pharmacists can assist clinicians to adjust the therapeutic regimen, and take effective interventions to the adverse drug reaction, improve the level of clinical drug treatment. Conclusion The clinical pharmacists take advantage of the pharmaceutical knowledge as the entry point,offer pharmaceutical care for patients timely and rationally, which ensure medication safety and efficacy．

Key words: voriconazole, hypokalemia, torsade de pointes(TdP), pharmaceutical care

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