中国药物警戒 ›› 2016, Vol. 13 ›› Issue (5): 306-308.

• 安全性评估与合理用药 • 上一篇    下一篇

我院门诊围绝经期女性激素用药分析

宋笑丹,张婧,马满玲   

  1. 哈尔滨医科大学附属第一医院药学部，黑龙江 哈尔滨150001
  • 收稿日期:2014-09-24 修回日期:2016-06-30 出版日期:2016-05-20 发布日期:2016-06-30
  • 通讯作者: 马满玲，女，主任药师，硕士，药理学与临床药学。E-mail：mamanling@126.com
  • 作者简介:宋笑丹，女，主管药师，硕士，临床药学。

Analysis of Utilization of Hormone Drugs in Perimenopausal Women in Outpatient of Our Hospital

SONG Xiao-dan, ZHANG Jing, MA Man-ling   

  1. Department of Pharmacy, First Affiliated Hospital of Harbin Medical University, Heilongjiang Harbin 150001, China
  • Received:2014-09-24 Revised:2016-06-30 Online:2016-05-20 Published:2016-06-30

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摘要： 目的 评价我院门诊围绝经期女性激素替代治疗药物的应用现状和相关问题。方法 采用回顾性分析，对我院2013年第一季度门诊围绝经期女性激素治疗药物的应用品种、销售金额、用药频度（DDDs）、日均费用（DDC）等进行统计、分析。结果 我院2月份门诊围绝经期女性患者激素用药销售金额、药品销售总金额及销售金额占药品销售总金额的比例均较低，各月份中，达芙通、克龄蒙、补佳乐和利维爱的销售金额、构成比始终居于前列，补佳乐所用比例呈逐月上升趋势，利维爱逐月下降。各月份中，补佳乐、克龄蒙、达芙通和欧维婷的使用频率始终处于前列，在各月份的DDC排序中，益玛欣和达芙通始终居高不下，利维爱也相对较高。结论 补佳乐、克龄蒙、达芙通和欧维婷是我院围绝经期女性激素替代治疗的常用药物，益玛欣和达芙通这两种药物对患者的经济负担较重。

关键词: 围绝经期, 激素替代治疗, 用药分析

Abstract: Objective To evaluate the status and issues of drugs related to hormone replacement therapy(HRT) in perimenopausal women in outpatient of our hospital. Methods The utilization of drugs related to HRT in perimenopausal women in outpatient of our hospital in the first quarter of 2013 was analyzed retrospectively in terms of varieties, consumption sum, DDDs, DDC, etc. Results The consumption sum of homone drugs in perimenopausal women, the total consumption sum and the ratio of the former to the latter in February 2013 were all lower. Duphaston, Climen, Progynova and Livial steadily dominated the first place on the consumption and constituent ratio lists in every month. The constituent ratio of Progynova showed an upward trend by month, while Livial was downward. Progynova, Climen, Duphaston and Ovestin were always on the top of the DDDs list in all months. In terms of DDC, Progesterone capsules and Duphaston ranked at the top 2 places in each month, followed by Livial. Conclusion Progynova, Climen, Duphaston and Ovestin were general drugs for HRT in perimenopausal women in our hospital. Progesterone capsules and Duphaston might be the heavy economic burden of patients.

Key words: perimenopause, hormone replacement therapy , analysis of drug utilization

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