中国药物警戒 ›› 2011, Vol. 8 ›› Issue (3): 184-186.

• 药品不良反应监测 • 上一篇    下一篇

汕头市4512例药品不良反应/事件报告分析

陈德梅1， 陈珮瑶2， 庄旭心3， 蔡德3   

  1. 1. 汕头市皮肤性病防治院,广东 汕头 515041;
    2. 汕头市中心医院,广东 汕头 515041;
    3. 汕头大学医学院第一附属医院,广东 汕头 515041
  • 收稿日期:2015-08-27 修回日期:2015-08-27 出版日期:2011-03-10 发布日期:2015-08-27
  • 通讯作者: 蔡德,男,主任药师,医院药学及相关研究。E-mail：stcaide@126.com
  • 作者简介:陈德梅,女,主管药师,医院药学。
  • 基金资助:
    汕府科（2009）70号

Analysis of 4512 Adverse Drug Reaction/Event Reports in Shantou

CHEN De-mei1, CHEN Pei-yao2, ZHUANG Xu-xin3, CAI-De3   

  1. 1. Shantou Municipal STD and Dermatosis Hospital, Guangdong Shantou 515041;
    2. Shantou Central Hospital, Guangdong Shantou 515041;
    3. The First Affiliated Hospital of Shantou University Medical College, Guangdong Shantou 515041, China
  • Received:2015-08-27 Revised:2015-08-27 Online:2011-03-10 Published:2015-08-27

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摘要： 目的 了解汕头市药品不良反应/事件的发生情况,分析其发生的因素、特点与规律,以期为临床合理用药提供参考,促进临床合理用药。方法 对汕头市药品不良反应中心提供的汕头市2006~2009年4 512例药品不良反应/事件报告进行统计分析。结果 4 512例药品不良反应/事件以中老年人不良反应发生率较高;涉及24类药物,以抗菌药物、中枢神经系统药物和中药制剂位居前三;临床表现以皮肤及其附件损害,全身性损害居多。结论 药品不良反应/事件与患者年龄,药品种类,给药方式等因素有关,应遵循合理用药原则,加强药品不良反应监测工作,促进临床合理用药。

关键词: 药品不良反应/事件, 分析

Abstract: Objective Understanding adverse drug reaction(ADR) of medicine in Shantou City, to analyze the factors, characteristics and rules that lead to ADR, for providing references of the reasonable Clinical Trail. Methods Statistics and analysis 4 512 cases of ADR reports that collected from 2006 to 2009 by center for ADR. Results Out of the 4 512 cases ADR reports, The high mortality was middle aged and elderly people ADR; The formor three drug among 24 kinds medicines were Antibiotics, Central nervous system drugs and TCM; The major clinical expressions of ADR were a general harm and skin and appendix harms. Conclusion The major factor of ADR were age,medicine kinds, the kind of take medicine, and so on. ADR monitoring should be followed the principles of take medicine and strengthened to promote the clinical use of drugs.

Key words: adverse drug reaction/event(ADR/ADE), analysis

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