某院老年肺部感染患者抗感染药应用现况调查

中国药物警戒 ›› 2011, Vol. 8 ›› Issue (2): 71-74.

某院老年肺部感染患者抗感染药应用现况调查

赵燕¹, 崔歆², 杨兴华², 张洪波³

1. 国家食品药品监督管理局药品评价中心,北京100045;
2. 首都医科大学公共卫生与家庭医学学院流行病与卫生统计学系,北京 100069;
3. 首都医科大学附属复兴医院干部保健科,北京 100045

收稿日期:2015-08-27 修回日期:2015-08-27 出版日期:2011-02-10 发布日期:2015-08-27
通讯作者: 杨兴华,女,副教授,流行病与卫生统计学。E-mail：xinghuay@263.net。张洪波,女,主治医师,内科疾病诊治。E-mail：chenpo67@sina.com
作者简介:赵燕,女,硕士,药物警戒与药品不良反应监测。
基金资助:
国家科技部重大新药创制/创新药物研究与开发技术体系建设专题（2010ZX09401）

A Cross-sectional Study on Existing Circumstance of Anti-infective Agents: Application for Elder Patients with Pulmonary Infections in a Certain Hospital

ZHAO Yan¹, CUI Xin², YANG Xing-hua², ZHANG Hong-bo³

1. Center for Drug Reevaluation, SFDA, Beijing 100045, China;
2. School of Public Health and Family Medicine, Capital Medical University, Beijing 100069, China;
3. Fu Xing Hospital, Capital Medical University, Beijing 100045, China

Received:2015-08-27 Revised:2015-08-27 Online:2011-02-10 Published:2015-08-27

摘要/Abstract

摘要： 目的通过对北京某医院干部病房老年肺部感染患者的回顾性调查,了解该人群抗感染药应用和老年肺部感染特点,探讨可能影响该人群肺部感染性疾病转归的危险因素。方法选取该医院2008~2009年干部病房收治的181名老年肺部感染住院患者的病例进行回顾性调查,采用SPSS17.0统计软件包进行统计分析处理。结果 181例老年患者平均年龄82.8±6.57岁,肺部感染性疾病如肺炎、慢性支气管炎、慢性阻塞性肺病（COPD）和急性支气管炎的治疗有效率分别为87.90%、95.10%、96.00%和71.40%。影响肺部感染转归的因素为患者年龄（P =0.062）、所患基础病种类（P =0.024）和是否连续使用抗感染药（P =0.020）,其OR值和95% CI分别为0.234（0.051,1.073）、0.223（0.061,0.819）和3.260（1.200,8.856）。结论影响该人群肺部感染治疗结局的因素有患者年龄、所患基础病种类和是否连续使用抗感染药。

关键词: 老年人, 肺部感染, 抗感染药

Abstract: Objective Understand current status of anti-infective agents application and main characteristics of pulmonary infections for elder subjects with pulmonary infections in the cadre wards in a certain hospital by investigating their charts. Discuss risk factors that may influence outcomes of pulmonary infections. Methods Investigate clinical charts of 181 elder patients retrospectively in the cadre wards in this hospital between 2008 and 2009. All data were analyzed by SPSS17.0 software package. Results The effective rate of pneumonia, chronic bronchitis, COPD and acute bronchitis is 87.90%, 95.10%, 96.00% and 71.40%, respectively. Factors that influence the outcomes of pulmonary infections are patients’ age(P =0.062), type of underlying disease(P =0.024) and the continuing use of anti-infective agents(P =0.020). The OR value and 95%CI of those factors are 0.234(0.051, 1.073), 0.223(0.061, 0.819) and 3.260(1.200, 8.856). Conclusion Factors that influence outcomes of pulmonary infections are age of patients, type of underlying disease and continuing use of anti-infective agents.

Key words: the elderly, pulmonary infection, anti-infective agents

中图分类号:

R916.695

赵燕, 崔歆, 杨兴华, 张洪波. 某院老年肺部感染患者抗感染药应用现况调查[J]. 中国药物警戒, 2011, 8(2): 71-74.

ZHAO Yan, CUI Xin, YANG Xing-hua, ZHANG Hong-bo. A Cross-sectional Study on Existing Circumstance of Anti-infective Agents: Application for Elder Patients with Pulmonary Infections in a Certain Hospital[J]. Chinese Journal of Pharmacovigilance, 2011, 8(2): 71-74.

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