罗库溴铵注射液致气道痉挛1例分析

doi:10.19803/j.1672-8629.20250652

中国药物警戒 ›› 2026, Vol. 23 ›› Issue (7): 817-819.
DOI: 10.19803/j.1672-8629.20250652

罗库溴铵注射液致气道痉挛1例分析

钱霞, 郭志刚^*, 郑利光

北京大学口腔医院药剂科,国家口腔医学中心,口腔疾病国家临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心,北京 100081

收稿日期:2025-09-12 出版日期:2026-07-15 发布日期:2026-07-16
通讯作者: ^*郭志刚,男,博士,副主任药师,临床药学与药事管理。E-mail：guozhigang0909@163.com
作者简介:钱霞,女,硕士,主管药师,临床药学与医院药品不良反应收集监测。
基金资助:
北京市自然科学基金资助项目（9204031）; 北京大学口腔医（学）院管理科研基金资助项目（2023GLJJ10）; 北京大学口腔医（学）院管理科研基金资助项目（2022GLJJ10）

One case of airway spasm caused by rocuronium bromide injection

Qian Xia, Guo Zhigang^*, Zheng Liguang

Department of Pharmacy, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering of Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China

Received:2025-09-12 Online:2026-07-15 Published:2026-07-16

摘要/Abstract

摘要： 目的探讨罗库溴铵注射液致气道痉挛不良反应特点,为临床安全用药提供参考。方法分析1例8岁患儿术中使用罗库溴铵注射液引起气道痉挛的不良反应病例,探讨罗库溴铵注射液致气道痉挛的不良反应与可能发生机制,并提出治疗建议。结果使用解除气道痉挛药物处理后,患儿逐渐好转。经查阅药品说明书和文献,经关联性分析,判断罗库溴铵注射液和气道痉挛的关联性为“可能”。结论临床麻醉期间应关注罗库溴铵注射液引起气道痉挛的风险,加强不良反应监测,保障患者的用药安全。

关键词: 罗库溴铵注射液, 气道痉挛, 肌松药, 药品不良反应

Abstract: Objective To investigate the characteristics of such adverse reactions as airway spasm induced by rocuronium bromide injection, and to provide a reference for safe medication. Methods One case of intraoperative airway spasm caused by rocuronium injection in an 8-year-old patient was analyzed. Based on literature, the related adverse reactions and possible mechanisms were studied while treatment regimens were recommended. Results After discontinuation of the drug and symptomatic treatment, the patient gradually improved. By reviewing drug instructions and literature, it was found that the correlations between rocuronium bromide injection and airway spasm were “possible”. Conclusion During clinical anesthesia, the risk of airway spasm caused by rocuronium bromide injection deserves attention to ensure the safety of patients.

Key words: Rocuronium Bromide Injection, Airway Spasm, Muscle Relaxant Drug, Adverse Drug Reaction

中图分类号:

R994.11

钱霞, 郭志刚, 郑利光. 罗库溴铵注射液致气道痉挛1例分析[J]. 中国药物警戒, 2026, 23(7): 817-819.

Qian Xia, Guo Zhigang, Zheng Liguang. One case of airway spasm caused by rocuronium bromide injection[J]. Chinese Journal of Pharmacovigilance, 2026, 23(7): 817-819.

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罗库溴铵注射液致气道痉挛1例分析

One case of airway spasm caused by rocuronium bromide injection

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