中国药物警戒 ›› 2025, Vol. 22 ›› Issue (12): 1424-1426.
DOI: 10.19803/j.1672-8629.20241035

• 安全与合理用药 • 上一篇    下一篇

阿立哌唑片致心境障碍患者痤疮1例分析

薛茜1, 舒燕萍1, 何恋2, 张乾2*   

  1. 1贵州省第二人民医院普通精神科（女）,贵州 贵阳 550004;
    2贵州省第二人民医院药剂科临床药学室,贵州 贵阳 550004
  • 收稿日期:2024-12-26 发布日期:2025-12-19
  • 通讯作者: *张乾,男,本科,副主任药师,临床药学。E-mail: 714237545@qq.com
  • 作者简介:薛茜,女,本科,主治医生,儿童青少年情绪障碍临床研究。
  • 基金资助:
    贵州省高层次创新型人才合同书（gzwjrs2022-013）; 国家自然科学基金资助项目（82460282）

One Case of Acne in a Patient with Mood Disorder Caused by Aripiprazole Tablets

XUE Qian1, SHU Yanping1, HE Lian2, ZHANG Qian2*   

  1. 1Department of General Psychiatry (for Females), the Second People's Hospital of Guizhou, Guiyang Guizhou 550004, China;
    2Department of Pharmacy, the Second People’s Hospital of Guizhou, Guiyang Guizhou 550004, China
  • Received:2024-12-26 Published:2025-12-19

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摘要： 目的 分析服用阿立哌唑片致痤疮的病例,为临床合理用药提供参考。方法 对1例心境障碍患者服用阿立哌唑片致痤疮的病例治疗过程进行讨论,并结合相关文献,分析痤疮的临床表现、产生机制、不良结果及治疗要点。结果 患者服用阿立哌唑后情绪好转,但出现痤疮,经因果关系判定为阿立哌唑引起的不良反应。经调整个体化用药方案,患者病情稳定,痤疮好转。结论 阿立哌唑致痤疮不良反应使患者存在容貌自卑感和社交障碍,导致用药依从性降低;用药期间应加强患者的药学监护,可通过调整治疗方案消除或缓解痤疮症状。

关键词: 阿立哌唑, 痤疮, 药品不良反应, 心境障碍, 药学监护

Abstract: Objective To analyze one case of acne caused by aripiprazole in order to provide a reference for safe and rational medications. Methods A personalized treatment plan and tips about medication were provided for a patient with acne caused by aripiprazole. The clinical manifestations, mechanism of occurrence, adverse outcomes and priorities of treatment of acne were analyzed based on literature. Results This case was a patient with mood disorder. After treatment with aripiprazole, the patient’s mood improved significantly, but acne appeared. The adverse reactions caused by aripiprazole were determined through causal relationships. By adjusting the personalized medication plan, the patient’s condition became stable and the symptoms of acne improved. Conclusion The adverse drug reactions of acne caused by aripiprazole can lead to a patient’s feelings of physical inferiority and social barriers, thereby reducing medication compliance. During medication, the patient ought to be given better pharmaceutical care. Symptoms of acne can be eliminated or mitigated by adjusting the treatment regimen.

Key words: Aripiprazole, Acne, Adverse Drug Reactions, Mood Disorder, Pharmaceutical Care

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