中国药物警戒 ›› 2025, Vol. 22 ›› Issue (2): 231-234.
DOI: 10.19803/j.1672-8629.20240905

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中药治疗布鲁氏菌病研究进展

梁晓1, 李丽, 徐霄龙3,4, 白颖璐3, 杨玉媚5, 祝勇6,7#, 刘清泉1,3,4,*   

  1. 1内蒙古医科大学中医学院,内蒙古 呼和浩特 010110;
    2首都医科大学附属北京中医医院肝病科,北京 100010;
    3首都医科大学附属北京中医医院急诊与危重症救治中心,北京 100010;
    4北京市中医药研究所病生理室,北京 100010;
    5北京中医药大学临床医学院,北京中医医院,北京 100029;
    6首都医科大学附属北京中医医院呼吸科,北京 100010;
    7北京中医医院内蒙古医院肺病科,内蒙古 巴彦淖尔 015000
  • 收稿日期:2024-11-19 出版日期:2025-02-17 发布日期:2025-02-17
  • 通讯作者: 刘清泉,男,教授·博导,主任医师,急危重症与新发突发传染病。E-mail:liuqingquan2003@126.com;#为共同通信作者。
  • 作者简介:梁晓,女,在读博士,中蒙医内科学。Δ为并列第一作者。
  • 基金资助:
    国家中医药多学科交叉创新团队项目(ZYYCXTD- D-202201); 国家中医药管理局高水平中医药重点学科建设项目; (zyyzdxk-2023001); 国家自然科学基金资助项目(82474428); 内蒙古自治区自然科学基金资助项目(2024MS08026); 祝氏过敏煎传承博士科研工作站项目

Advancements in Treatment of Brucellosis with Traditional Chinese Medicine

LIANG Xiao1, LI Li, XU Xiaolong3,4, BAI Yinglu3, YANG Yumei5, ZHU Yong6,7#, LIU Qingquan1,3,4,*   

  1. 1The Traditional Chinese Medicine College, Inner Mongolia Medical University, Hohhot Inner Mongolia 010110, China;
    2Department of Hepatology, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China;
    3Emergency and Critical Care Center, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China;
    4Pathophysiology Laboratory, Beijing Institute of Traditional Chinese Medicine, Beijing 100010, China;
    5The Clinical Medical College (Beijing Hospital of Traditional Chinese Medicine), Beijing University of Chinese Medicine, Beijing 100029, China;
    6Department of Respiratory Medicine, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China;
    7Department of Pulmonary Disease, Inner Mongolia Hospital Beijing Hospital of Traditional Chinese Medicine, Bayannur Inner Mongolia 015000, China
  • Received:2024-11-19 Online:2025-02-17 Published:2025-02-17

摘要: 目的 布鲁氏菌病是一种因感染引起的传染性人畜共患疾病,常累及多个脏腑器官,慢性期迁延难愈。为补充现代医药的不足,寻求其更加安全有效的治疗方案。方法 通过对近年来中药治疗布鲁氏菌病的相关文献进行梳理归纳,基于病因辨证、伤寒六经辨证、八纲辨证、卫气营血辨证共4个辨证体系对布鲁氏菌病用药及组方进行分类探讨。结果与结论 经总结布鲁氏菌病的总体治法分为急、慢性期2个阶段,用药思路涉及六经、卫气营血。根据不同辨证思路予以中药治疗,具有较好的临床效果,为今后布鲁氏菌病的中药研究和临床用药提供参考。

关键词: 布鲁氏菌病, 中药, 辨证体系, 宣痹汤, 小柴胡汤

Abstract: Objective To seek safer and more effective treatment options against brucellosis, which is an infectious zoonotic disease involving multiple organs and systems. Methods Literature related to the treatment of brucellosis with Traditional Chinese Medicine (TCM) in recent years was reviewed. Based on four diagnostic systems - etiological differentiation, six-meridian syndrome differentiation of treatise on febrile diseases, eight-line syndrome differentiation, and wei-qi-ying-xue differentiation, the medications and formula composition for brucellosis were categorized. Results and Conclusion The treatment of brucellosis is divided into acute and chronic phases, with medications involving the six-meridian syndrome differentiation and the wei-qi-ying-xue differentiation. TCM has shown good clinical effects. This study is expected to provide a reference for future research on and clinical medications for brucellosis with TCM.

Key words: Brucellosis, Traditional Chinese Medicine, Differentiation Systems, Xuanbi Decoction, Xiaochaihu Decoction

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