中国药物警戒 ›› 2025, Vol. 22 ›› Issue (3): 341-342.
DOI: 10.19803/j.1672-8629.20240677

• 安全与合理用药 • 上一篇    下一篇

多次口服头孢氨苄胶囊后合用乌龙茶致过敏性休克1例分析

伏箫燕1, 苟瑜2, 罗先海2, 胡巧织3,*   

  1. 1成都市新都区人民医院药学部,四川 成都 610500;
    2成都北新医院内科,四川 成都 610500;
    3四川大学华西医院药剂科,四川 成都 610000
  • 收稿日期:2024-08-30 出版日期:2025-03-15 发布日期:2025-03-17
  • 通讯作者: *胡巧织,女,硕士,主管药师,临床药学。E-mail：447811112@qq.com
  • 作者简介:伏箫燕,女,硕士,主管药师,药物警戒。
  • 基金资助:
    四川省科技厅自然科学基金资助项目（2023NSFSC1696）

One Case of Anaphylactic Shock Caused by Multiple Oral Cephalexin Capsules Combined with Oolong Tea

FU Xiaoyan1, GOU Yu2, LUO Xianhai2, HU Qiaozhi3,*   

  1. 1Department of Pharmacy, Xindu District People’s Hospital of Chengdu, Chengdu Sichuan 610500, China;
    2Medical Department, Chengdu Beixin Hospital, Chengdu Sichuan 610500, China;
    3Department of Pharmacy, West China Hospital, Sichuan University, Chengdu Sichuan 610000, China
  • Received:2024-08-30 Online:2025-03-15 Published:2025-03-17

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摘要： 目的 探讨多次使用头孢氨苄胶囊后导致过敏性休克的可能原因,为临床安全用药提供参考。方法 结合文献分析1例37岁女性多次口服头孢氨苄胶囊,1个月再次使用该药并合用乌龙茶后出现过敏性休克的可能原因。结果 该患者发生过敏性休克的原因复杂,可能与头孢氨苄所致超敏反应及食物相互作用有关。结论 使用头孢类抗生素需密切关注药品不良反应,使用过该类药物且未发生不良反应也应予以重视。

关键词: 头孢氨苄胶囊, 过敏性休克, 药品不良反应, 相互作用

Abstract: Objective To explore the possible causes of anaphylactic shock after repeated use of cephalexin and to provide a reference for safe clinical use. Methods The possible causes of anaphylactic shock in a 37-year-old woman who had taken cephalexin capsules orally several times and then used the drug together with oolong tea one month later were analyze based on related literature. Results The cause of anaphylactic shock in this patient was unclear, which might be related to hypersensitivity caused by cephalexin and interactions between foods. Conclusion The use of cephalosporin antibiotics demands close attention to adverse drug reactions. Clinicians ought to monitor patients who have used this drug but have developed no adverse reactions.

Key words: Cephalexin Capsules, Anaphylactic Shock, Adverse Drug Reaction, Interaction

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