中国药物警戒 ›› 2015, Vol. 12 ›› Issue (3): 178-181.

• 医院药事管理与合理用药 • 上一篇    下一篇

头孢哌酮/舒巴坦致骨科围术期患者药物热的病例分析与药学监护

蓝晓红,周永刚,赵红军   

  1. 解放军第八一医院，江苏 南京 210002
  • 收稿日期:2014-11-05 出版日期:2015-03-08 发布日期:2015-07-28
  • 通讯作者: 周永刚，男，主任药师，药剂学与临床药学。
  • 作者简介:蓝晓红，女，主管药师，心血管药理与临床药学。

Case Analysis and Pharmaceutical Care of Drug Fever Induced by Cefoperazone/Sulbactam for Perioperative Patient in Department of Orthopedics

LAN Xiao-hong,ZHOU Yong-gang,ZHAO Hong-jun   

  1. 81st Hospital of PLA, Jiangsu Nanjing 210002, China
  • Received:2014-11-05 Online:2015-03-08 Published:2015-07-28

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摘要： 目的 探讨临床药师在头孢哌酮/舒巴坦致药物热中的作用及药学监护点。方法 对我院发生的的头孢哌酮/舒巴坦致药物热不良反应的典型病例和相关文献进行分析。结果 考虑到该患者高热原因不能用感染、吸收热和下肢静脉血栓等原因解释，停用头孢哌酮/舒巴坦，5天后患者未再出现发热。结论 临床药师参与药物热的治疗，有助于临床及时准确地判断患者病情，防止误诊、误治，提高抗菌药物的用药合理性，避免医疗资源的浪费。

关键词: 头孢哌酮/舒巴坦, 药物热, 骨科, 围术期感染

Abstract: Objective To investigate the role of the clinical pharmacist in the treatment of patients with dug fever induced by cefoperazone sulbactam and the focus of pharmaceutical care. Methods We analyzed the related literatures and typical case of drug fever induced by cefoperazone sulbactam occurred in our hospital. Results Considering that the causes of high fever could not be explained by infection, absorption heat and venous thrombosis of lower extremity, the intravenous drip of cefoperazone sulbactam was stopped, temperature of the patient returned to normal 5 days later. Conclusion If clincal pharmacists participate in the treatment of drug fever, it can help to judge patients' condition accurately, avoid misdiagnosis, mistreatment and wasting medical resources, and improve rational use of antimicrobial drugs.

Key words: cefoperazone sulbactam, drug fever, department of orthopedics, perioperative infection

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