中国药物警戒 ›› 2014, Vol. 11 ›› Issue (8): 501-503.

• 综述 • 上一篇    下一篇

临床药师参与1例药物性肝损害患者的药物分析与调整

黄海花1, 2, 邓昂1, 孔旭东1, 唐, 崑1*   

  1. 1中日友好医院药学部,北京100029;
    2湖南省邵阳市第一人民医院药剂科,湖南 邵阳422000
  • 收稿日期:2016-02-03 修回日期:2016-02-03 出版日期:2014-08-08 发布日期:2016-03-02
  • 通讯作者: 唐,女,本科,副主任药师,临床药学。E-mail:tangkun7332@126.com
  • 作者简介:黄海花,女,硕士,药师,临床药学及药理学。

Clinical Pharmacists Participating in Drug Analysis and Adjustment for a Patient with Drug-induced Liver Injury

HUANG Hai-hua1, 2, DENG Ang1, KONG Xu-dong1, TANG Kun1, *   

  1. 1Department of Pharmacy, China-Japan Friendship Hospital, Beijing 100029, China;
    2Department of Pharmacy, First People's Hospital of Shaoyang, Hunan Shaoyang 422000, China
  • Received:2016-02-03 Revised:2016-02-03 Online:2014-08-08 Published:2016-03-02

摘要: 目的为临床药师在肾内科参与药物性肝损害患者的治疗提供参考。方法临床药师参与1例药物性肝损害患者的药物治疗方案的分析与调整,充分考虑患者年龄、肾病综合征伴低钾血症、血行播散型肺结核的特点,建议医师停用可疑药物,调整保肝药物。结果临床药师结合患者特点,从药物相互作用及不良反应方面,积极配合医师,为患者提供了合理的用药方案。经治疗后,患者肝功能得以恢复。结论肾内科临床药师参与临床实践,可从药学的角度发挥优势,优化治疗方案。

关键词: 临床药师, 药物分析, 肾内科, 药物性肝损害

Abstract: ObjectiveTo provide reference for nephrology clinical pharmacist participating in the therapy for a patient with drug-induced liver injury. MethodsClinical pharmacists participated in analysis and adjustment of therapeutic scheme for a patient with drug-induced liver injury. In consideration of the characteristics of the patient,such as the age, nephrotic syndrome with hypokalemia and miliary tuberculosis, it is suggested that physician discontinued the suspicious drugs and adjusted the liver protective drugs. ResultsTaking the characteristics of the patient into consideration, clinical pharmacists assisted physician actively to provide reasonable drug therapy scheme for patient from drug interaction and adverse reaction. The liver function of the patient recovered after treatment. ConclusionClinical pharmacist in nephrology department participating in clinical practice can play advantages from the perspective of pharmacy to optimize therapeutic scheme.

Key words: clinical pharmacist, drug analysis, nephrology department, drug-induced liver injury

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