中国药物警戒 ›› 2014, Vol. 11 ›› Issue (1): 50-53.

• 医院药事管理与合理用药 • 上一篇    下一篇

综合干预对围手术期抗菌药物预防使用的影响

崔敏,钟晗,苏颖杰,逄晓云,刘晓琰*   

  1. 上海交通大学医学院附属仁济医院药剂科,上海 200127
  • 收稿日期:2016-02-03 修回日期:2016-02-03 出版日期:2014-01-08 发布日期:2016-02-03
  • 通讯作者: 刘晓琰,女,硕士,副主任药师,临床药学。
  • 作者简介:崔敏,女,硕士,主管药师,临床药学。

Effects of Comprehensive Interventions on Preventive Use of Antibacterials During Perioperative Period

CUI Min, ZHONG Han, SU Ying-jie, PANG Xiao-yun, LIU Xiao-yan*   

  1. Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University,Shanghai 200127, China
  • Received:2016-02-03 Revised:2016-02-03 Online:2014-01-08 Published:2016-02-03

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摘要： 目的比较干预前后我院清洁手术预防使用抗菌药物情况,为进一步规范我院围手术期预防使用抗菌药物提供依据。方法采用回顾性调查方法,以2010年第1季度为干预前基础数据,以2011年第1季度和2012年第1季度为干预后数据,从各时间段中随机选取甲状腺、乳腺、腹外疝手术病例各100份,统计、分析、比较干预前后围手术期预防使用抗菌药物情况,评价综合干预成效。结果抗菌药物预防使用率干预后持续下降,由2010年的89.3%下降到2011年的55.0%和2012年的20.0%（P <0.01）,抗菌药费用明显减少（P<0.01）,用药合理性明显提高。结论我院为规范围手术期预防使用抗菌药物采取的综合干预措施可行、有效。

关键词: 综合干预, 清洁手术, 预防使用抗菌药物, 围手术期

Abstract: ObjectiveIn order to standardize preventive use of antibacterials during perioperative period in our hospital, a control study was conducted to compare the preventive use of antibacterials in aseptic operation before-and-after interventions. MethodsAccording to retrospective method, 300 cases were randomly selected from the first quanter of 2010, the first quanter of 2011 and the first quanter of 2012, respectively. The preventive use of antibacterials in aseptic operation was analyzed and evaluated. ResultsAfter the intervention, the proportion of cases using antibacterial was obviously reduced, the antibacterial cost was decreased significantly, the rationality of antibacterial use was obviously enhanced. ConclusionThe comprehensive intervention measures to optimize the preventive use of antibacterials during perioperative period in our hospital are effective and feasible.

Key words: comprehensive intervention, aseptic operation, preventive use of antibacterials, perioperative period

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