中国药物警戒 ›› 2025, Vol. 22 ›› Issue (9): 1054-1056.
DOI: 10.19803/j.1672-8629.20240940

• 安全与合理用药 • 上一篇    下一篇

铝碳酸镁咀嚼片致严重过敏反应1例分析

邵一帆1, 陈秋岑2, 翟惠奇1, 吴伟2, 褚庆民2,*   

  1. 1广州中医药大学第一临床医学院,广东 广州 510405;
    2广州中医药大学第一附属医院心血管科,广东 广州 510405
  • 收稿日期:2024-12-04 发布日期:2025-09-22
  • 通讯作者: *褚庆民,男,博士,副主任医师,中医内科学。E-mail: 13929504676@163.com
  • 作者简介:邵一帆,男,在读硕士,中医内科学。
  • 基金资助:
    广东省基础与应用基础研究基金项目（2023A15-15220158）; 广东省基础与应用基础研究基金项目（2022A15-15220138）; 广东省医学会临床科研专项基金项目（A202301022）

One Case of Severe Allergic Reactions Caused by Hydrotalcite Chewable Tablets

SHAO Yifan1, CHENG Qiucen2, ZHAI Huiqi1, WU Wei2, CHU Qingmin2,*   

  1. 1Graduate School, the First Clinical Medical College of Guangzhou University of Traditional Chinese Medicine, Guangzhou Guangdong 510405, China;
    2Department of Cardiology, the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou Guangdong 510405, China
  • Received:2024-12-04 Published:2025-09-22

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摘要： 目的 探讨铝碳酸镁咀嚼片引起的严重过敏反应,为临床提供参考。方法 分析1例术后使用铝碳酸镁咀嚼片预防消化道损伤致严重过敏反应的病例,通过国内外文献讨论不良反应发生机制、临床表现和治疗等。结果 经关联性分析,该不良反应与用药存在合理时间关系,属于Ⅱ级严重过敏反应,患者经抗过敏、升压、补液治疗后症状缓解。结论 临床应警惕铝碳酸镁咀嚼片导致的严重过敏反应,但其导致严重过敏反应机制尚不清楚,需进一步研究。

关键词: 铝碳酸镁咀嚼片, 过敏反应, 药品不良反应

Abstract: Objective To explore serious allergic reactions caused by hydrotalcite chewable tablets so as to provide a reference for clinical practice. Methods One case was analyzed in which hydrotalcite chewable tablets were used after surgery to prevent severe allergic reactions caused by digestive tract injury. The mechanism of occurrence, clinical manifestations, and treatment of sub-adverse reactions were investigated based on literature. Results Correlation analysis found that there was a close relationship between the time this adverse reaction occurred and the time of medication. The adverse reaction was classified as a grade II severe allergic reaction. This patient’s symptoms improved after treatment with anti-allergy drugs, blood pressure elevation and rehydration. Conclusion Clinicians should be alert to severe allergic reactions caused by hydrotalcite chewable tablets. The related mechanism remains elusive and more studies are needed.

Key words: Hydrotalcite Chewable Tablets, Anaphylaxis, Adverse Drug Reaction

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