中国药物警戒 ›› 2013, Vol. 10 ›› Issue (1): 42-43.

• 药械安全性研究 • 上一篇    下一篇

45例莫西沙星不良反应病例分析

邬丹莲,陈志高,窦文琴,陈婷婷   

  1. 东南大学医学院附属江阴人民医院药剂科,江苏江阴 214400
  • 收稿日期:2012-06-04 修回日期:2016-03-12 出版日期:2013-01-08 发布日期:2016-03-09
  • 作者简介:邬丹莲,女,药师,药理学硕士,临床药学。

Analysis of 45 Cases of ADR Induced by Moxifloxacin

WU Dan-lian, CHEN Zhi-gao, DOU Wen-qin ,CHEN Ting-ting   

  1. The Affiliated Jiangyin Hospital of Southeast University Medical College, Jiangsu Jiangyin 214400, China
  • Received:2012-06-04 Revised:2016-03-12 Online:2013-01-08 Published:2016-03-09

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摘要： 目的 探讨莫西沙星不良反应的一般规律和特点,为减少不良反应发生率及临床合理用药提供参考。方法 对 2009年至2011年我院的45例莫西沙星不良反应按照性别、年龄、给药途径等方法进行统计与分析。结果 近3年我院莫西沙星不良反应逐年增加,2011年增加量尤为明显,其中新的严重的不良反应所占比例增加,皮肤黏膜类不良反应所占比例升高且女性不良反应发生例数显著增加,年龄因素对莫西沙星不良反应的影响每年基本相似。结论临床应重视莫西沙星的不良反应,特别注意皮肤黏膜不良反应的发生,及早做好应对措施。

关键词: 莫西沙星, 药品不良反应, 皮肤黏膜, 性别

Abstract: Objective To investigate the general rules and characteristics of moxifloxacin's adverse reaction, so as to provide advice for reducing adverse reaction rate. Method We analysed the moxifloxacin's adverse reaction from 45 inpatients during 2009~2011. Result The number of moxifloxacin's adverse reaction has increased year by year during recent three years, especially 2011. Meanwhile, the percentage of the new and serious ADR, the cutaneous and mucosa ADR and the woman ADR was significantly increased. Conclusion The doctors need to pay attention to moxifloxacin's adverse reaction, especially skin and mucosa ADR.

Key words: moxifloxacin, adverse drug reaction, skin and mucosa, gender

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