中国药物警戒 ›› 2017, Vol. 14 ›› Issue (11): 687-690.

• 安全性评价与合理用药 • 上一篇    下一篇

1例肺癌化疗所致急性肝损伤患者的药学监护

游丽娜1, 姜坤2*   

  1. 1 昆明市延安医院药学部,云南 昆明 650051;
    2 云南昆钢医院药学部,云南 昆明 650302
  • 收稿日期:2017-07-26 修回日期:2017-12-26 出版日期:2017-11-20 发布日期:2017-12-26
  • 通讯作者: *姜坤,男,本科,主管药师,临床药学。E-mail:163jiangkun520@163.com
  • 作者简介:游丽娜,女,硕士,主管药师,临床药学。

Pharmaceutical Care for Chemotherapy-induced Acute Liver Injury in a Patient with Lung Cancer

YOU Li-Na1, JIANG Kun2,*   

  1. 1 Department of Pharmacy, Yan'an Hospital of Kunming City, Yunnan Kunming 650051, China;
    2 Department of Pharmacy, Yunnan Kungang Hospital, Yunnan Kunming 650302, China
  • Received:2017-07-26 Revised:2017-12-26 Online:2017-11-20 Published:2017-12-26

摘要: 目的 探讨临床药师对肺癌化疗所致急性肝损伤患者实施药学监护的方法和意义。方法 临床药师通过参与1例肺癌化疗所致急性肝损伤患者的治疗过程,对不良反应及时监测,从保肝药物的选择以及引起急性肝损伤药物的再次应用问题为患者提供药学监护。结果 临床药师参与药物治疗,可发挥专业特长,协助医师调整用药方案,提高临床药物治疗水平。结论 临床药师在临床工作中,应积极发挥作用,与临床医师协作,积极开展药品不良反应监测工作,并注意收集相关国内外文献报道,采取有效干预措施,共同促进合理用药,提高医疗水平。

关键词: 化疗, 急性肝损伤, 临床药师, 药学监护

Abstract: Objective To explore the methods and significance of providing pharmaceutical care for lung cancer patients with chemotherapy-induced acute liver injury by clinical pharmacist. Methods By participating in drug therapy for a lung cancer patient with chemotherapy-induced acute liver injury, pay close attentions on the patients and make reasonable suggestions as to the adverse drug reactions to guarantee the rational use of drug. Clinical pharmacist provided pharmaceutical care such as selection of hepatoprotective drugs and the reapplication of drugs that cause acute liver injury for patients. Results Clinical pharmacists can assist clinicians to adjust the therapeutic regimen from the perspective of pharmacists, and improve the level of clinical drug treatment. Conclusion In clinical work, clinical pharmacists should play its due role in collaboration with clinicians actively, and carry out the monitoring of adverse drug reactions. In order to promote rational drug use and improve health treatment, we should take effective interventions.

Key words: chemotherapy, acute liver injury, clinical pharmacist, pharmaceutical care

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