复合异丙酚麻醉诱导时舒芬太尼抑制患者喉罩插管反应的药效学价值

中国药物警戒 ›› 2017, Vol. 14 ›› Issue (10): 587-589.

复合异丙酚麻醉诱导时舒芬太尼抑制患者喉罩插管反应的药效学价值

王志玮

辽宁省鞍山市中心医院麻醉科，辽宁鞍山114001

收稿日期:2016-11-21 修回日期:2017-11-30 出版日期:2017-10-20 发布日期:2017-11-30
作者简介:王志玮，男，本科，副主任医师，临床麻醉

Pharmacodynamic Value of Sufentanil Inhibiting Laryngeal Mask Intubation Reaction Induced by Compound Propofol Anesthesia

WANG Zhi-wei

Department of Anesthesiology, Central Hospital of Anshan City, Liaoning Anshan 114001, China

Received:2016-11-21 Revised:2017-11-30 Online:2017-10-20 Published:2017-11-30

摘要/Abstract

摘要： 目的探讨复合异丙酚麻醉诱导时舒芬太尼抑制患者喉罩插管反应的药效学价值。方法收集我院2014年1月至2015年12月入院的80例行全麻非腔镜手术患者随机分为两组，研究组患者采取异丙酚诱导+舒芬太尼，对照组患者采取异丙酚诱导+芬太尼，比较两组患者不同时点脑电双频指数、血压与心率、不良反应与诱导时间。结果两组患者不同时点脑电双频指数、血压与心率均不存在明显差异，不具有统计学意义（P＞0.05）；研究组患者总体不良反应发生率（12.5%）明显低于对照组（32.5%），存在明显差异，具有统计学意义（P＜0.05）；两组患者麻醉诱导时间不存在明显差异，不具有统计学意义（P＞0.05）。结论复合异丙酚麻醉诱导时舒芬太尼抑制患者喉罩插管反应的药效学价值较高，具有借鉴性。

关键词: 异丙酚, 舒芬太尼, 喉罩插管反应, 麻醉诱导

Abstract: Objective To investigate the pharmacodynamic value of sufentanil inhibiting laryngeal mask insertion reaction in the induction of propofol anesthesia. Methods 80 patients undergoing general anesthesia were randomly divided into two groups: research group received propofol induced+sufentanil and control group received propofol induced +fentanyl, compared between two groups of patients at different points of bis, blood pressure and heart rate, adverse reactions and induction time. Results There was no significant difference in blood pressure and heart rate between the two groups at different time points (P >0.05). The incidence of overall adverse reaction in research group was significantly lower than that in control group, and there was significant difference (P <0.05). There was no significant difference in the induction time of anesthesia between the two groups (P >0.05). Conclusion The inhibitory effect of sufentanil on the intubation of laryngeal mask is high in the induction of propofol anesthesia.

Key words: propofol, sufentanil, laryngeal mask intubation reaction, induction of anesthesia

中图分类号:

R971.1

王志玮. 复合异丙酚麻醉诱导时舒芬太尼抑制患者喉罩插管反应的药效学价值[J]. 中国药物警戒, 2017, 14(10): 587-589.

WANG Zhi-wei . Pharmacodynamic Value of Sufentanil Inhibiting Laryngeal Mask Intubation Reaction Induced by Compound Propofol Anesthesia[J]. Chinese Journal of Pharmacovigilance, 2017, 14(10): 587-589.

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