中国药物警戒 ›› 2011, Vol. 8 ›› Issue (5): 302-305.

• 综述 • 上一篇    下一篇

非甾体抗炎药所致肠道损伤

罗佳, 王惠吉, 郝瑞瑞   

  1. 首都医科大学附属北京友谊医院综合科,北京100050
  • 收稿日期:2015-08-27 修回日期:2015-08-27 出版日期:2011-05-10 发布日期:2015-08-27
  • 作者简介:罗佳,女,硕士,临床医学。

The Injury of Intestinal Tract Induced by the NSAIDs

LUO Jia, WANG Hui-Ji, HAO Rui-rui   

  1. Beijing Friendship Hospital, Capital Medical University, General Division, Beijing 100050, China
  • Received:2015-08-27 Revised:2015-08-27 Online:2011-05-10 Published:2015-08-27

摘要: 非甾体抗炎药(NSAIDs)是目前临床应用最广泛、处方中最常见的药物之一,但此类药物治疗作用与不良反应并存,不恰当的应用或滥用,会给患者造成严重危害。大量研究表明NSAIDs不仅可以引起胃的损伤,也可以引起肠道的损伤,甚至比上消化道更为严重,应引起临床医师警惕。

关键词: 非甾体抗炎药, 肠道损伤, 发病机制, 治疗方案

Abstract: Non steroidal-anti-inflammatory drugs(NSAIDs) is the clinical application of the most widely prescribed drugs the most common one, but the therapeutic effects of these drugs and adverse reactions exist, inappropriate application or abuse, would cause serious harm to patients. Numerous studies show that NSAIDs not only cause damage to the stomach can also cause intestinal damage, and even more serious than the upper digestive tract, should alert the clinicians.

Key words: NSAIDs, small intestinal injury, pathogenesis, treatment

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