中国药物警戒 ›› 2015, Vol. 12 ›› Issue (6): 330-331.

• 基础及临床研究 • 上一篇    下一篇

自制紫草浸膏外用治疗大鼠烫伤实验研究

王勇,王双艳,肖晏婴,   

  1. 湖北中医药大学附属襄阳医院药学部，湖北 襄阳 441000
  • 收稿日期:2014-09-15 出版日期:2015-06-08 发布日期:2015-07-27
  • 作者简介:王勇，男，本科，主管药师，药库管理与合理用药。

Experimental Study of Topical Homemade Extract of Lithospermum Erythrorhizon Treating Scalded Rats

WANG Yong,WANG Shuang-yan,XIAO Yan-ying   

  1. Pharmacy Department, Xiangyang Hospital Affiliated to Hubei University of Chinese Medicine, Hubei Xiangyang 441000, China
  • Received:2014-09-15 Online:2015-06-08 Published:2015-07-27

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摘要： 目的 开展紫草浸膏治疗大鼠烫伤的药效学实验，明确其外用治疗烫伤的功能。方法 选取SD大鼠60只，随机分成5组，恒温水浴烫伤大鼠右足造模，用软皮尺测量大鼠足趾周长，计算肿胀率。结果 紫草高、低浓度组与对照组相比较有统计学差异（P＜0.05）。结论 自制紫草浸膏外用，对热水所致烫伤有一定的疗效，适宜临床推广应用。

关键词: 紫草, 浸膏, 外用, 烫伤

Abstract: Objective To study the pharmacological effects of Lithospermum erythrorhizon on scalded rats in order to clarify its topical treatment function of burns. Methods 60 rats were randomly divided into 5 groups． We used the constant temperature water bath to manufacture rat burn model and measured the rat paw circumference with a soft tape measure. Foot swelling rate was evaluated with computer. Results Compared with the control group, there were significant differences in Lithospermum erythrorhizon high, low concentration group (P<0.05). Conclusion Homemade extract of Lithospermum erythrorhizon could treat hot water scaldand be suitable for clinical application.

Key words: Lithospermum erythrorhizon, extract, external use, scald

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