艾司氯胺酮注射液致震颤不良反应1例分析

doi:10.19803/j.1672-8629.20250096

中国药物警戒 ›› 2025, Vol. 22 ›› Issue (10): 1174-1176.
DOI: 10.19803/j.1672-8629.20250096

艾司氯胺酮注射液致震颤不良反应1例分析

苏甦¹, 王莫伊^2△, 马艺溢³, 李晓玲¹, 褚燕琦¹, 张兰^1,*

¹首都医科大学宣武医院药学部,北京 100053;
²首都医科大学药学院,北京 100069;
³暨南大学附属第一医院,广州华侨医院药学部,广东广州 510630

收稿日期:2025-02-18 出版日期:2025-10-15 发布日期:2025-10-20
通讯作者: ^*张兰,女,博士,主任药师,药事管理。E-mail: xwzhanglan@163.com
作者简介:苏甦,女,硕士,副主任药师,临床药学与老年多重用药。^△为并列第一作者。
基金资助:
药物不良反应杂志《2024年药物安全研究项目》（ADR2024MS14）; 首都医科大学本科生科研创新项目（XSKY2024439）; 中国研究型医院学会专项课题项目（Y2024FH-YWPJ02）

One Case of Tremor Caused by Esketamine Injection

SU Su¹, WANG Moyi^2△, MA Yiyi³, LI Xiaoling¹, CHU Yanqi¹, ZHANG Lan^1,*

¹Department of Pharmacy, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
²School of Pharmaceutial Sciences, Capital Medical University, Beijing 100069, China;
³Department of Pharmacy, the First Affiliated Hospital of Jinan University, Guangzhou Overseas Chinese Hospital, Guangzhou Guangdong 510630, China

Received:2025-02-18 Online:2025-10-15 Published:2025-10-20

摘要/Abstract

摘要： 目的探讨艾司氯胺酮注射液致震颤不良反应的特点,为临床安全用药提供参考。方法分析1例术中使用艾司氯胺酮致震颤的不良反应病例,通过关联性评价和查阅文献对艾司氯胺酮致震颤的不良反应及产生机制进行分析,并提出治疗建议。结果经查阅药品说明书和文献,判断艾司氯胺酮与震颤的关联性为可能。停药后,患者逐渐好转。结论临床应关注艾司氯胺酮引起震颤的风险,加强不良反应监测,保障患者的用药安全。

关键词: 艾司氯胺酮, 注射液, 震颤, 药品不良反应, 药学监护, 麻醉药物

Abstract: Objective To study the characteristics of esketamine-induced tremors and to provide references for safe medications. Methods One case of tremor caused by esketamine was studied. The adverse reactions and pathogenesis of tremors caused by esketamine were analyzed based on correlation evaluation and literature review. Recommendations about treatment and the priorities of pharmaceutical care were outlined. Results After the drug instructions and related literature were reviewed, the correlation between esketamine and tremors was determined as “possible”. The symptoms were gradually improved after discontinuation of esketamine. Conclusion Clinicians should be aware of the risk of tremors caused by esketamine and monitor for adverse reactions of esketamine to ensure the safety of patients.

Key words: Esketamine, Injection, Tremor, Adverse Drug Reactions, Pharmaceutical Care, Anesthetic

中图分类号:

R994.11

苏甦, 王莫伊, 马艺溢, 李晓玲, 褚燕琦, 张兰. 艾司氯胺酮注射液致震颤不良反应1例分析[J]. 中国药物警戒, 2025, 22(10): 1174-1176.

SU Su, WANG Moyi, MA Yiyi, LI Xiaoling, CHU Yanqi, ZHANG Lan. One Case of Tremor Caused by Esketamine Injection[J]. Chinese Journal of Pharmacovigilance, 2025, 22(10): 1174-1176.

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https://zgywjj.magtechjournal.com/CN/Y2025/V22/I10/1174

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艾司氯胺酮注射液致震颤不良反应1例分析

One Case of Tremor Caused by Esketamine Injection

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