中国药物警戒 ›› 2019, Vol. 16 ›› Issue (7): 404-410.

• 中药药物警戒与合理用药专栏 • 上一篇    下一篇

《本草纲目》药物防毒警戒思想研究

石琳1,2, 刘欣1,2, 张冰1,2,*   

  1. 1 北京中医药大学,北京 100029;
    2 北京中医药大学中药药物警戒与合理用药研究中心,北京 100029
  • 收稿日期:2019-08-06 修回日期:2019-08-06 出版日期:2019-07-20 发布日期:2019-08-06
  • 通讯作者: 张冰,女,教授、主任医师·博导,中药药物警戒与合理用药研究、中药药性研究。E-mail：zhangbing6@263.net
  • 作者简介:石琳,女,博士,副研究员,中药药物警戒与合理用药研究。
  • 基金资助:
    国家自然科学基金（81874349）：辛热类有毒中药风险-效益阈与效毒机制研究

Study on Prevention of Drug Toxicity in Pharmacovigilance Thought of the Compendium of Materia Medica

SHI Lin1,2, LIU Xin1,2, ZHANG Bing1,2,*   

  1. 1 Beijing University of Chinese Medicine, Beijing 100029, China;
    2 Center for Pharmacovigilance and Rational Use of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
  • Received:2019-08-06 Revised:2019-08-06 Online:2019-07-20 Published:2019-08-06

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摘要： 目的 从药物警戒的角度对《本草纲目》进行研究,挖掘整理其中蕴含的中药药物警戒思想和实践经验。方法 用传统文献的研究方法,对《本草纲目》中关于药物来源与辨伪、产地与采收、加工与炮制、防范已知的药物不良反应等防毒警戒内容进行归纳整理。结果 形成《本草纲目》药物防毒警戒思想体系。结论 《本草纲目》防毒警戒思想主要体现在药物的种属及鉴别、药物炮制、不良反应记录三个方面。

关键词: 《本草纲目》, 防毒, 警戒思想

Abstract: Objective To study the Compendium of Materia Medica from the perspective of pharmacovigilance, mine and reorganize the pharmacovigilance thought of Chinese medicine and practical experiences in it. Methods By using traditional literature research methods, contents of prevention of drug toxicity in pharmacovigilance of the Compendium of Materia Medica, such as source and distinguishing, origin and harvest, processing, and prevention of adverse drug reactions etc. were summed up. Results Ideological system of prevention of drug toxicity of the Compendium of Materia Medica was formed. Conclusion There are mainly three aspects of prevention of drug toxicity in pharmacovigilance thought of the Compendium of Materia Medica, which are attaching great importance to species and distinguishing, processing and records of adverse drug reactions.

Key words: Compendium of Materia Medica, prevention of drug toxicity, pharmacovigilance thought

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